Treatment of Atopic Dermatitis
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Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting approximately 10% of the US population. AD often occurs as a childhood disease in conjunction with allergies and asthma, but it can also persist into or arise de novo in adulthood. AD negatively affects quality of life, social interactions, and work productivity, with annual US health care costs exceeding $5.3 billion.1 The current guideline provides recommendations on the management of AD in adults with both nonpharmacologic and pharmacologic topical therapies
A 50-year-old man presented to the dermatology department with a 1-year history of itchy axillary and groin lesions. He had been treated with a topical antifungal preparation (cyclopyroxolamin), without improvement, by his family physician, who had suspected fungal intertrigo. On physical examination, we observed well-circumscribed, erythematous, brownish, scaly plaques affecting both armpits and the groin area bilaterally (Figure 1). To rule out superficial mycoses, we examined skin scrapings from the infected site under direct microscopy after potassium hydroxide preparation. We did not find any signs of fungal infection and did not isolate any dermatophytes in Sabouraud agar.