Endometriosis, a common cause of pelvic pain, affects approximately 10% of reproductive-age females. Author Sawsan As-Sanie, MD, MPH, University of Michigan, discusses the epidemiology, pathophysiology, diagnosis, and treatment of endometriosis with JAMA Senior Editor Karen E. Lasser, MD, MPH....
Recent Resources
Low Back Pain A Review
Abstract
Importance Low back pain is defined as pain localized below the costal margin and above the inferior gluteal fold, with or without leg pain. Low back pain affects approximately 619 million people worldwide and is the leading cause of years lived with disability worldwide.
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Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults A WikiGuidelines Group Consensus Statement
Importance Traditional approaches to practice guidelines frequently result in dissociation between strength of recommendation and quality of evidence.
Objective To create a clinical guideline for the diagnosis and management of urinary tract infections that addresses the gap between the...
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Evaluating Inflammatory Joint Pain in Older Adults-Practical Diagnostic Clues for Primary Care Clinicians
Arthritis is a leading cause of pain and disability that affects nearly one-third of older US adults (age ≥65 years). While osteoarthritis (OA) predominates, many have inflammatory arthritis (IA), including rheumatoid arthritis (RA), spondyloarthritis, and crystal arthropathies.1 Recognition of...
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Adult Male Hypogonadism: A Review
Importance Male hypogonadism is a clinical syndrome of signs and symptoms of testosterone deficiency and consistently low morning serum testosterone concentrations. The prevalence of hypogonadism due to hypothalamus, pituitary, or testes pathology is less than 1%, and the prevalence due to...
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Hearing Aids for Adults With Mild to Moderate Hearing Loss
Hearing loss is defined as an impaired ability to hear sounds at thresholds considered to be normal. Projections based on audiometric data from the National Health and Nutrition Examination Survey estimate that by 2030, approximately 55 million US adults will have hearing loss, including 35...
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Approach to Fatigue in Primary Care: A Practical Diagnostic Framework for General Practitioners
Fatigue is one of the most common presenting complaints in primary care and poses a significant diagnostic challenge due to its multifactorial aetiology. While the majority of cases are benign and self-limiting, fatigue may also represent an early manifestation of serious underlying pathology....
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Tramadol versus placebo for chronic pain: a systematic review with meta-analysis and trial sequential analysis
Objectives The objective of our study was to assess the benefits and harms of tramadol vs placebo in adults with chronic pain.
Design The research method was a systematic review of randomised clinical trials with meta-analysis. The review followed the Trial Sequential Analysis and the...
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Autism-Understanding Diagnosis, Prevalence, and Treatment: A Healthy Dialogue With Jeremy Veenstra-VanderWeele and Dost Öngür
Autism spectrum disorder (ASD) remains a topic of intense public interest, with debates over rising diagnosis rates, questions about causes, and new developments in treatments and outcomes. In the first episode of Healthy Dialogue, a new podcast from the JAMA Network, I sit down with JAMA...
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Hepatitis B: A Review
Importance: Hepatitis B virus (HBV) infection affects an estimated 254 million people worldwide and causes approximately 1.1 million deaths annually. In 2022, there were approximately 1.2 million new HBV infections worldwide and 14 000 in the US.
Observations: HBV is a DNA virus...
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