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Pharmacologic Treatment of Heart Failure With Reduced Ejection Fraction: An Updated Systematic Review and Network Meta-Analysis

Author/s: Bart J. van Essen, Daan C.H. Ceelen, Wouter Ouwerkerk, Tiew-Hwa K. Teng, Ganash N. Tharshana, Fook Ming Hew, Javed Butler, Faiez Zannad, Carolyn S. Lam, Justin Ezekowitz, Adriaan A. Voors, Jasper Tromp

Background: In 2022, a network meta-analysis showed that a combination of β-blockers, angiotensin receptor-neprilysin inhibitors (ARNi), mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter 2 inhibitors (SGLT2i) was most effective in reducing all-cause mortality in...

Keywords/Tags:
HFrEF drug therapy pharmacotherapy

What RSV Is and Why Immunization Matters

Author/s: Alistair Mukondiwa, Callie L. Brown, Lindsay A. Thompson

This JAMA Pediatrics Patient Page describes respiratory syncytial virus (RSV) in children and how to prevent its spread.
Keywords/Tags:
pediatrics RSV respiratory synytial virus vaccines immunizations vaccines

Use of Ambient AI Scribes to Reduce Administrative Burden and Professional Burnout

Author/s: Kristine D. Olson, Daniella Meeker, Matt Troup

Importance: While in short supply and high demand, ambulatory care clinicians spend more time on administrative tasks and documentation in the electronic health record than on direct patient care, which has been associated with burnout, intention to leave, and reduced quality of care.

...

Keywords/Tags:
burnout burnout, professional ambulatory care ambient AI

What Parents Should Know About Preventing Accidental Poisonings

Author/s: Mickey A Emmanuel, Ava Mascarenhas, Lindsay A Thompson

This JAMA Pediatrics Patient Page discusses the most common causes of poisoning in children and safety tips to prevent poisoning.
Keywords/Tags:
Poison Poison Control analgesics Accidental Consumption

Online Unsupervised Tai Chi Intervention for Knee Pain and Function in People With Knee Osteoarthritis: The RETREAT Randomized Clinical Trial

Author/s: Shiyi Julia Zhu, Rana S Hinman, Rachel K Nelligan, Peixuan Li, Anurika P De Silva, Jenny Harrison, Alexander J Kimp, Kim L Bennell

Importance: Tai chi is a type of exercise recommended for knee osteoarthritis, but access to in-person tai chi can be limited.

Objective: To evaluate the effects of an unsupervised multimodal online tai chi intervention on knee pain and function for people with knee osteoarthritis.

...
Keywords/Tags:
Knee osteoarthritis kinesiophobia Tai Chi

Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis

Author/s: Lei Yan, Dijun Li, Dan Xing, Zijuan Fan, Guangyuan Du, Jingwei Jiu, Xiaoke Li, Janne Estill, Qi Wang, Ahmed Atef Belal, Chen Tian, Jiao Jiao Li, Songyan Li, Haifeng Liu, Xuanbo Liu, Yijia Ren, Yiqi Yang, Jinxiu Chen, Yihe Hu, Long Ge, Bin Wang

Objective: To assess the efficacy and safety of various exercise modalities as therapeutic interventions for managing knee osteoarthritis.

Design: Systematic review with network meta-analysis.

Data sources: PubMed, Embase, Cochrane Library, Web of Science, CINAHL, PsycINFO, AMED,...

Keywords/Tags:
exercise exercise therapy Knee osteoarthritis

What Do I Need to Know About the Pneumococcal Pneumonia Vaccine?

Author/s: Jerard Z. Kneifati-Hayek, Michael A. Incze

What Is the Pneumococcal Pneumonia Vaccine?
The pneumococcal vaccine protects against infections from a type of bacteria called pneumococcus. Pneumococcus is a common cause of pneumonia (a lung infection), as well as other serious infections. The vaccine prepares your immune system to...

Keywords/Tags:
'Vaccination Infectious diseases Patient Information Pneumococcal Vaccines

Efficacy and safety of respiratory syncytial virus vaccines

Author/s: K M Saif-Ur-Rahman, Catherine King, Seán Olann Whelan, Matthew Blair, Seán Donohue, Caoimhe Madden, Kavita Kothari, Isolde Sommer, Thomas Harder, Nicolas Dauby, Ida Rask Moustsen-Helms, Simona Ruta, Julie Frère, Viktoria Schönfeld, Eero Poukka, Irja Lutsar, Kate Olsson, Angeliki Melidou, Karam Adel Ali, Kerry Dwan, Declan Devane

Rationale: Respiratory syncytial virus (RSV) is a highly transmissible pathogen that causes varying degrees of respiratory illness across all age groups. The safety and efficacy profiles of available RSV vaccines, a critical consideration for their integration into public health strategies and...

Keywords/Tags:
vaccine efficacy respiratory synytial virus vaccines

The effectiveness and safety of methotrexate in the intervention of osteoarthritis: A systematic review and meta-analysis of randomized controlled trials

Author/s: Wan, Lifei, Yang, Qianyue, Yang, Kailin, Zeng, Liuting, Sun, Lingyun

Background:
Osteoarthritis (OA) is a prevalent chronic joint disorder among middle-aged and older adults, characterized by progressive cartilage degeneration, subchondral bone remodeling, and osteophyte formation, leading to joint pain, stiffness, dysfunction, and reduced quality of life....

Keywords/Tags:
methotrexate osteoarthritis meta-analysis systematic review

What Parents Should Understand About Lipid Screening in Children

Author/s: Michael Silverstein, Michael J Barry, Lindsay A Thompson

This JAMA Pediatrics Patient Page describes what parents should consider in deciding whether to have their child screened for high lipid levels.
Keywords/Tags:
Lipids child parents

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