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AAP Releases Its Own Childhood and Adolescent Immunization Schedule

Author/s: Samantha Anderer

The AAP recommends vaccines to protect children against 18 diseases. The updated CDC schedule removed routine recommendations for hepatitis A and B, COVID-19, respiratory syncytial virus, rotavirus, influenza, and meningococcal disease, instead only recommending them for certain groups at high...

Keywords/Tags:
Immunization Schedule Respiratory Syncytial Viruses Human Papillomavirus Viruses vaccines Combined Chickenpox Vaccine Rubella Vaccine

Medications for essential tremor

Author/s: Allison Paige, Samantha S. Moe

Clinical question
How effective are β-blockers and other first-line agents for essential tremor?

Bottom line
Older, small randomized controlled trials (RCTs) show that propranolol reduces tremor severity (about 2 points more than placebo on 10- to 15-point scales) and leads to...

Keywords/Tags:
essential tremor Upper Limb Tremor propranolol Sotalol Metoprolol Primidone Topiramate atenolol

Approach to mallet finger injury: Practical guide for Canadian primary care physicians

Author/s: Vincent Dinh, Marisa Market, Kevin Cheung

Objective: To provide primary care physicians with an evidence-based approach to recognizing and managing mallet finger injuries.

Sources of information: A literature search was conducted in PubMed and Google Scholar using relevant key words and subject headings. Recommendations were...

Keywords/Tags:
Finger Injuries Mallet Finger Hand injuries Hand Deformities Splints Tendon Injuries

Medications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose: A Review

Author/s: Miriam T H Harris, Zoe M Weinstein, Alexander Y Walley

Importance: Opioid use disorder (OUD) involves compulsive opioid use that causes substantial distress or impairment at work, school, or home. OUD, which is the third most prevalent substance use disorder worldwide, affected an estimated 3.7% of US adults (9 367 000) in 2022 and caused 53 774...

Keywords/Tags:
Opiates Opioid Use Disorder opioid abuse opioid overdose methadone

Hypertension and alcohol: a cross-sectional study comparing PEth with AUDIT and AUDIT-C in primary care

Author/s: Åsa Thurfjell, Maria Hagströmer, Charlotte Ivarsson, Anders Norrman, Johanna Adami, Lena Lundh, Jan Hasselström

Background: This cross-sectional study aimed to describe proportions of patients with indications of alcohol consumption using phosphatidylethanol (PEth), the Alcohol Use Disorders Identification Test (AUDIT), and its consumption-focused version (AUDIT-C), in relation to blood pressure (BP)...

Keywords/Tags:
alcohol use disorder cardiovascular disorders hypertension prevention primary care screening

Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review and Meta-Analysis

Author/s: Nazmul Islam, Alexandro W L Chu, Falana Sheriff, Farid Foroutan, Gordon H Guyatt, Romina Brignardello-Petersen, Paul Oykhman, Alfonso Iorio, Ariel Izcovich, Katherine M Morrison, Yetiani Roldan Benitez

Importance: The incidence and risk (predictive) factors for early life food allergy development remain uncertain.

Objective: To estimate the incidence and quantify risk factors for food allergy development.

Data sources: MEDLINE and Embase were systematically searched to January 1...

Keywords/Tags:
Food Allergies Development antibiotics children infant Allergies Allergens Food Hypersensitivity

The association between medication use and vitamin B12 deficiency in the elderly population: a cross- sectional study

Author/s: Monique P H Tillemans, Thijs J Giezen, Toine C G Egberts, Kees J Kalisvaart

Background
Vitamin B12 deficiency is common in the elderly population and can cause severe complications. The use of certain medication has in previous studies been associated with vitamin B12 deficiency in the general population. To identify elderly patients at risk for vitamin B12...

Keywords/Tags:
metformin Metformin Treatment anticonvulsants Antacids Vitamin B 12 Deficiency

Management of Premenstrual Disorders

Author/s: Rebeca Ortiz Worthington, Lindsey M Eastman, Jason T Alexander

Premenstrual disorders encompass a spectrum of cyclic affective and physical symptoms that interfere with daily functioning, occurring during the luteal phase and resolving with or immediately following menstruation. Premenstrual disorders may be caused by fluctuations of estrogen in the luteal...

Keywords/Tags:
Premenstrual Dysphoric Disorder Luteal Phase menstruation Affective Symptoms

HEADSSS Assessment

Author/s: Dr Nicola Martin, Dr Louise Ingram, Adam Bonfield

The HEADSSS assessment is an internationally recognised tool used to structure the assessment of an adolescent patient, encompassing Home, Education/Employment, Activities, Drugs, Sex and relationships, Self harm and depression, Safety and abuse. The assessment starts with simple and easy...

Keywords/Tags:
adolescent Drug abuse Relationships safety abuse Self Harm assessment depression

Exacerbation risk in patients with bronchiectasis receiving DPP-1 inhibitors vs placebo: A meta-analysis of RCTs

Author/s: Giulia Carvalhal, Júlia Moreira Diniz, Larissa Calixto Hespanhol, David Curi Barbosa Izoton Cabral, Jafar Aljazeeri

Background: No therapies have been approved to alter bronchiectasis progression. Dipeptidyl peptidase-1 (DPP-1) inhibitors, which target neutrophil serine protease activation, are under investigation as potential disease-modifying agents.

Methods: We conducted a systematic review and meta...

Keywords/Tags:
Bronchiectasis DPP-1 inhibitor Dipeptidyl-peptidases and tripeptidyl-peptidases meta-analysis

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