Deprecated: Return type of DrupalCacheArray::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 362

Deprecated: Return type of DrupalCacheArray::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home/rprlib/prod72/www/includes/bootstrap.inc on line 369

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Beyond Avoidance: Omalizumab and the Evolving Care of Pediatric Food Allergy

Author/s: Lolita Alocer Alkureishi, Sai R. Nimmagadda, Joseph R. Hageman

Food allergy is familiar territory in primary care, but the therapeutic landscape is changing quickly. For years, our conversations with families centered on avoidance, label reading, emergency action plans, and ready access to epinephrine. Those remain essential. Yet, newer therapies now offer...

Keywords/Tags:
Pediatric Food Allergies omalizumab children

Management of Shoulder Pain in Primary Care

Author/s: Romi Haas, Thomas Ibounig, Rachelle Buchbinder

Importance Shoulder pain is a common and disabling condition most often managed in primary care. This review provides an evidence-based update on the diagnosis and management of shoulder pain to support clinical decision-making and improve patient outcomes.

Observations Shoulder pain...

Keywords/Tags:
Shoulder Pain primary care soft-tissue disorders

Fasting Duration and Differences Across Routine Laboratory Tests

Author/s: Sunghwan Shin, Sollip Kim, Shinae Yu, Soo Jin Yoo, Kuenyoul Park, Jeonghyun Chang, Tae-Hyun Um, Chong Rae Cho, Dong Hee Whang

Abstract
Importance Fasting before blood collection is widely practiced to reduce preanalytical variability, yet whether fasting-related differences are clinically meaningful across a broad panel of routine analytes has not been systematically evaluated using clinical data.

...

Keywords/Tags:
fasting Routine Analytes laboratory testing Blood Work

Actions Reported by Physicians With Large Improvements in Burnout and Professional Fulfillment

Author/s: Tait D. Shanafelt, MD, Maryam S. Makowski, PhD, Brook Hale, et al.

Importance Occupational distress among physicians is a highly prevalent problem that limits the effectiveness of the health care delivery system. While system change is necessary, individual physicians must also consider personal actions to mitigate occupational distress.

Objective To...

Keywords/Tags:
burnout, professional Occupational Distress Qualitative Study Mixed-Methods Approach U.S. Health Study

Projected Benefit of Bilateral Salpingo-Oophorectomy by Age in BRCA Carriers

Author/s: Vasily Giannakeas, PhD, Adriana I. Apostol, MD, Claudia Diella, et al.

Importance Women with a BRCA1 or BRCA2 variant face a high lifetime risk of ovarian cancer and are often advised to undergo preventive surgery (bilateral salpingo-oophorectomy [BSO]) before cancer develops. The recommended age of BSO is 35 years for BRCA1 carriers and is 45 years for BRCA2...

Keywords/Tags:
Women's Health Bilateral Salpingo-Oophorectomy ovarian cancer BRCA carriers clinical study BSO BRCA variants

Idiopathic Normal Pressure Hydrocephalus A Review

Author/s: S. Farzad Maroufi, Sevil Yasar, Abhay Moghekar, Mark G. Luciano

Abstract
Importance Idiopathic normal pressure hydrocephalus (iNPH) is a progressive neurological disorder characterized by cerebral ventricular enlargement that is typically associated with gait impairment and often urinary dysfunction and cognitive decline in older adults. iNPH...

Keywords/Tags:
Idiopathic Normal Pressure Hydrocephalus neurology cognitive assessment

Pulmonary Nodules

Author/s: Matthew E.J. Callister, Gerard Silvestri

Pulmonary nodules are classified as solid or subsolid, with subsolid nodules further classified as part-solid or pure ground-glass. Management strategies differ according to the type of nodule. A comparison of current and previous imaging studies, when available, is essential to assess the risk...

Keywords/Tags:
pulmonary nodules breathing difficulties adenomatous hyperplasia

Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults

Author/s: Sophia Zoungas, Rory Wolfe, Chris Moran, Stephen J. Nicholls, Geoffrey C. Cloud, Christopher M. Reid, Andrew M. Tonkin, Lawrence Beilin, Anthony S. Wierzbicki, Trevor T.-J. Chong, Jonathan C. Broder, Andrea J. Curtis, Zachary Flanagan, Ingrid Hopper, Joanne Ryan, Simone Spark, John J. McNeil, Mark R. Nelson

Abstract
Background
The effectiveness and safety of statins for the primary prevention of cardiovascular events and the extension of disability-free survival among older adults remain uncertain.
Methods
We conducted a double-blind, randomized, placebo-controlled trial at...

Keywords/Tags:
Atorvastatin cardiovascular events statins

Blood pressure measurement techniques

Author/s: Tony Nickonchuk, Adrienne J. Lindblad, Danielle Perry, Scott Garrison

Do recommended blood pressure (BP) measurement techniques impact the accuracy of readings?

Cuff size, arm position, bladder distention, and leg crossing affect systolic BP (SBP) and diastolic BP (DBP) measurement accuracy (1 mm Hg lower to 20 mm Hg higher). Thin clothing does not impact...

Keywords/Tags:
blood pressure measurements accuracy

Rheumatoid Arthritis in Adults

Author/s: Josef S. Smolen, Andreas Kerschbaumer, Daniel Aletaha

Importance Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and destruction of cartilage and adjacent bone and can lead to irreversible disability. Rheumatoid arthritis affects 0.53% of adults worldwide and 0.74% of US adults.

Observations Rheumatoid...

Keywords/Tags:
Arthritis, Rheumatoid Inflammation synovial joints

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