Narcolepsy

Author/s: 
Kiran P. Maski, Thomas Scammell
Date Added: 
September 11, 2026
Journal/Publication: 
JAMA
Publisher: 
The American Medical Association
Publication Date: 
September 9, 2026
Pages: 
E1-E2
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
doi: 10.1001/jama.2026.14685

RPR Commentary

RPR Commentary: A concise review of what we currently understand about narcolepsy. James W. Mold, MD, MPH

Abstract

Narcolepsy is a chronic neurologic disorder that causes severe daytime sleepiness and impaired quality of life. Symptoms typically begin around age 10 to 20 years, yet diagnosis is often delayed for more than a decade.1 Narcolepsy is classified into narcolepsy type 1 (NT1; narcolepsy with cataplexy) and narcolepsy type 2 (NT2; narcolepsy without cataplexy), with estimated global prevalences of 19 and 23 per 100 000 persons, respectively.2

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