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Narcolepsy

Author/s: 
Kiran P. Maski, Thomas Scammell

Narcolepsy is a chronic neurologic disorder that causes severe daytime sleepiness and impaired quality of life. Symptoms typically begin around age 10 to 20 years, yet diagnosis is often delayed for more than a decade.1 Narcolepsy is classified into narcolepsy type 1 (NT1; narcolepsy with cataplexy) and narcolepsy type 2 (NT2; narcolepsy without cataplexy), with estimated global prevalences of 19 and 23 per 100 000 persons, respectively.2

Keywords 
Narcolepsy brain hypothyroidism

What Is Narcolepsy?

Author/s: 
Sum-Ping, O., Mignot, E.

Narcolepsy is a chronic disorder that causes excessive daytime sleepiness
and other symptoms that are due to abnormal rapid eye movement (REM) sleep.
Other signs and symptoms:
• Quick transitions into REM sleep
• Vivid dreams, hallucinations, and sleep paralysis
• Cataplexy (sudden, short periods of muscle weakness triggered
by strong emotions, typically laughter) in narcolepsy type 1
Narcolepsy type 1 occurs when the hypothalamus produces little or no orexin,
a hormone that helps maintain wakefulness and controls REM (dreaming) sleep.
Narcolepsy type 2 does not have a known cause.

Keywords 
Sleep Paralysis Narcolepsy Wakefulness Emotions Hallucinations
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