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Has This Child Experienced Physical Abuse? The Rational Clinical Examination Systematic Review

Author/s: Sonal N Shah, Hiu-Fai Fong, Suzanne B Haney, Mary Clyde Pierce, Nancy S Harper, Mark I Neuman

Importance: Nearly 100 000 children experience physical abuse each year in the US. Among approximately 2000 annual deaths related to child maltreatment, more than 40% resulted from physical abuse, and half of those children were younger than 1 year. Many of these young children had unidentified...

Keywords/Tags:
The Rational Clinical Examination Trauma and Injury child abuse Psychiatry and Behavioral Health Child and Adolescent Psychiatry

Prenatal Cannabis Use and Neonatal Outcomes A Systematic Review and Meta-Analysis

Author/s: Jamie O Lo, Chelsea K Ayers, Snehapriya Yeddala, Beth Shaw, Shannon Robalino, Rachel Ward, Devan Kansagara

Importance: Prenatal cannabis use continues to increase, and cannabis remains the most commonly used illegal substance in pregnancy. Accumulating evidence suggests potential adverse effects on fetal and neonatal outcomes following cannabis use in pregnancy.

Objective: To update a living...

Keywords/Tags:
Pregnancy prenatal cannabis cannabis cannabis use infants

Management of Peripheral Artery Disease

Author/s: Aman Kansal, MD, Andrew M. Davis, MD, MPH, Jennifer A. Rymer, MD, MBA

This JAMA Clinical Guidelines Synopsis summarizes the American College of Cardiology and American Heart Association’s 2024 guidelines on management of lower extremity peripheral artery disease.
Keywords/Tags:
guidelines surgery vascular surgery peripheral arterial disease Cardiology

Management of Peripheral Artery Disease

Author/s: Aman Kansal, MD, Andrew M. Davis, MD, MPH, Jennifer A. Rymer, MD, MBA

This JAMA Clinical Guidelines Synopsis summarizes the American College of Cardiology and American Heart Association’s 2024 guidelines on management of lower extremity peripheral artery disease.
Keywords/Tags:
guidelines surgery vascular surgery peripheral arterial disease Cardiology

Screening for Intimate Partner Violence and Caregiver Abuse of Older or Vulnerable Adults

Author/s: US Preventive Services Task Force Recommendation Statement, Michael Silverstein, John B Wong, Esa M Davis, David Chelmow, Tumaini Rucker Coker, Alicia Fernandez, Ericka Gibson, Carlos Roberto Jaén, Marie Krousel-Wood, Sei Lee, Wanda K Nicholson, Goutham Rao, John M Ruiz, James Stevermer, Joel Tsevat, Sandra Millon Underwood, Sarah Wiehe

IMPORTANCE: Intimate partner violence (IPV) affects millions of US residents across the lifespan and is often unrecognized. Abuse of older or vulnerable adults by a caregiver or someone else they may trust is common and can result in significant injury, death, and long-term adverse health...

Keywords/Tags:
intimate partner violence abuse caregiver abuse Adults

Inhaled Pharmacotherapy for Stable COPD

Author/s: Nathan C Nowalk, Andrew M Davis, Krysta S Wolfe

This JAMA Clinical Guidelines Synopsis summarizes the 2025 Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations for inhaled pharmacotherapy for stable COPD.
Keywords/Tags:
lung disease copd

Diagnosis and Treatment of Type 2 Diabetes in Adults A Review

Author/s: Rita R Kalyani, Joshua J Neumiller, Nisa M Maruthur, Deborah J Wexler

Importance: Type 2 diabetes involves progressive loss of insulin secretion from pancreatic β cells in the setting of insulin resistance and manifests clinically as hyperglycemia. Type 2 diabetes accounts for 90% to 95% of all cases of diabetes globally, with estimates ranging from 589 million to...

Keywords/Tags:
diabetes type 2 diabetes treatment

New Frontier, New Challenges—Recognizing and Managing Adverse Effects of Antiamyloid Therapies

Author/s: Megan A Rech, Neelum T Aggarwal, Ula Hwang

This clinical insight discusses the diagnosis and management of adverse effects of antiamyloid therapies and what medications require consideration or avoidance.
Keywords/Tags:
antiamyloid therapies

Early Invasive or Conservative Strategies for Older Patients With Acute Coronary Syndromes: A Meta-Analysis

Author/s: Rohin K Reddy, David Koeckerling, Christian Eichhorn, Yasser Jamil, Maddalena Ardissino, Volker Braun, Haitham Abu Sharar, Norbert Frey, James P Howard, Yousif Ahmad

Importance: The optimal management strategy for older patients who present with acute coronary syndrome (ACS) remains unclear due to a paucity of randomized evidence. New large and longer-term randomized data are available.

Objective: To test the association of an early invasive strategy...

Keywords/Tags:
stroke older patients heart heart failure

Occupational Heat-Related Illness

Author/s: June T Spector, Coralynn S Sack, David K Bonauto

This JAMA Insights proposes solutions to help reduce the risk of heat-related illnesses among workers.
Keywords/Tags:
heat illnesses occupational disease

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