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University of Oklahoma Health Sciences Center

Cervical cancer screening guideline for individuals at average risk

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Author/s: 
Chor, J., Davis, A. M., Rusiecki, J. M.
Date Added: 
November 14, 2021
Journal/Publication: 
JAMA
Publication Date: 
November 12, 2021
Type: 
Meta-analyses, Reviews, and Guidelines
DOI (1): 
10.1001/jama.2021.13448

RPR Commentary

The American Cancer Society’s most recent recommendations regarding cervical cancer screening.

Abstract

Major recommendations

Begin screening at age 25 years regardless of sexual history or HPV vaccination status (strong recommendation)

Primary HPV testing every 5 years through age 65 years (strong recommendation)

If primary HPV testing is not available use cotesting (HPV+ cytology) every 5 years or every 3 years if cytology only (strong recommendation)

Discontinue screening at age 65 years if no history of cervical intraepithelial neoplasia grade 2 or more severe diagnosis in last 25 years and adequate negative prior screening in last 10 years (qualified recommendation)