University of Oklahoma Health Sciences Center

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Author/s:

John M. Eisenberg Center for Clinical Decisions and Communications Science

Date Added:

October 23, 2018

Journal/Publication:

AHRQ Comparative Effectiveness Reviews

Publisher:

Agency for Healthcare Research and Quality

Publication Date:

July 26, 2016

URL:

Diagnosis of Celiac Disease: Current State of the Evidence

Type:

Meta-analyses, Reviews, and Guidelines, Meta-analyses, Reviews, and Guidelines

Format:

Article

PMID (1):

27583323

Keywords

celiac disease

sensitivity and specificity

clinical decision-making

MeSH

celiac disease

sensitivity and specificity

clinical decision-making

RPR Commentary

This is a summary of the evidence regarding how to diagnose celiac disease.

Abstract

This is a summary of a systematic review evaluating the evidence regarding the comparative accuracy (the balance of sensitivity and specificity) and possible adverse consequences (both direct and indirect) of various methods used to diagnose celiac disease. The systematic review included 60 individual studies and 13 previous systematic reviews published from January 1990 through March 2015. The full report, listing all studies and reviews, is available at www.effectivehealthcare.ahrq.gov/celiac-disease. This summary is provided to assist in informed clinical decisionmaking. However, reviews of evidence should not be construed to represent clinical recommendations or guidelines.

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