University of Oklahoma Health Sciences Center

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Author/s:

Jiha Lee, Justin B Levinson, Una E Makris

Date Added:

June 16, 2026

Journal/Publication:

JAMA Intern Med

Publisher:

The American Medical Association

Publication Date:

June 8, 2026

URL:

Evaluating Inflammatory Joint Pain in Older Adults-Practical Diagnostic Clues for Primary Care Clinicians

Type:

Meta-analyses, Reviews, and Guidelines

CME Credits:

Format:

Article

DOI (1):

doi: 10.1001/jamainternmed.2026.2032

Keywords

Arthritis, Rheumatoid

osteoarthritis

older adults

MeSH

RPR Commentary

RPR Commentary: A review of the evaluation of older patients with joint inflammation. James W. Mold, MD, MPH

Abstract

Arthritis is a leading cause of pain and disability that affects nearly one-third of older US adults (age ≥65 years). While osteoarthritis (OA) predominates, many have inflammatory arthritis (IA), including rheumatoid arthritis (RA), spondyloarthritis, and crystal arthropathies.1 Recognition of IA is frequently delayed for longer than a year in older adults due to atypical and overlapping presentations.2 Untreated IA can lead to irreversible damage, functional decline, and prolonged glucocorticoid exposure. Joint pain is often initially evaluated by primary care clinicians; therefore, timely recognition and early management are essential. This article highlights unique aspects of IA in older adults and offers practical guidance.

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