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University of Oklahoma Health Sciences Center

Exercise as a treatment for depression

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Author/s: 
Carl Zhou, Nicholas Fabiano
Date Added: 
May 14, 2024
Journal/Publication: 
Canadian Medical Association Journal
Publisher: 
Canadian Medical Association
Publication Date: 
May 5, 2024
Issue: 
17
Volume: 
196
Pages: 
E596-E96
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1503/cmaj.231288
PMID (1): 
38719220

RPR Commentary

Supervised exercise works as well as and more consistently (NNT=2) then antidepressants in adults with depression. James W. Mold, MD, MPH

Abstract

Exercise effectively treats depression and may decrease suicide attempts

A 2023 meta-analysis of randomized controlled trials (RCTs) found that supervised, group or non-group, moderate- or vigorous-intensity, aerobic or resistance exercises (excluding mind–body activities such as yoga) decreased depressive symptoms among participants with depression, with a number needed to treat of 2 and an effectiveness comparable to first-line treatments such as psychotherapy and medication. Another 2023 meta-analysis of RCTs found that exercise decreased suicide attempts among people with mental or physical illness.

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