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University of Oklahoma Health Sciences Center

Menopausal Hormone Therapy

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Author/s: 
Shifren, Jan L., Crandall, Carolyn J., Manson, JoAnn E.
Date Added: 
June 5, 2019
Journal/Publication: 
JAMA
Publisher: 
American Medical Association
Publication Date: 
May 30, 2019
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1001/jama.2019.5346

RPR Commentary

A concise review of post-menopausal hormonal therapies.  James W. Mold, MD, MPH

Abstract

Hormone therapy is the most effective treatment for managing menopausal vasomotor symptoms. Hot flashes and night sweats affect approximately 70% of midlife women and may persist for a decade or longer.1 Bothersome vasomotor symptoms have a significant adverse effect on sleep, daily functioning, and quality of life. Cognitive and mood symptoms often accompany disruptive hot flashes. Although lifestyle changes and nonhormonal options are available, women with frequent, severe vasomotor symptoms may greatly benefit from hormone therapy.2

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