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Preexposure Prophylaxis (PrEP) for HIV

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Author/s: 
Matthew A Spinelli, Kenneth Ngure, Monica Gandhi
Date Added: 
October 23, 2024
Journal/Publication: 
JAMA
Publication Date: 
October 14, 2024
URL: 
Preexposure Prophylaxis (PrEP) for HIV
Type: 
Meta-analyses, Reviews, and Guidelines
Format: 
Article
DOI (1): 
10.1001/jama.2024.16984
PMID (1): 
39401050
Keywords 
prophylaxis
Anti-HIV Agents
HIV
MeSH 
acquired immunodeficiency syndrome
antiviral agents
HIV infections

RPR Commentary

A concise review of pre-exposure prophylaxis for HIV. James W, Mold, MD, MPH

Abstract

Preexposure prophylaxis (PrEP) involves use of antiviral medication for HIV prevention in HIV-negative adults or adolescents at risk for HIV through sex or injection drug use. The United Nations Programme on HIV/AIDS (UNAIDS) recently set a goal for 95% of people at risk of HIV (approximately 10 million people worldwide) to have access to and use PrEP in 2025, although only 3.5 million individuals at risk of HIV were receiving PrEP as of 2023. The UNAIDS 2024 global AIDS update reported no decrease in HIV incidence since 2021, with an estimated 1.3 million new infections reported globally in 2023.

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