University of Oklahoma Health Sciences Center

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Author/s:

Mia Derstine, Elan Small, Andrew M Davis

Date Added:

October 28, 2024

Journal/Publication:

JAMA

Publisher:

American Medical Association

Publication Date:

October 24, 2024

URL:

Prevention, Diagnosis, and Treatment of Acute Altitude Illness

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1001/jama.2024.19562

PMID (1):

39446318

Keywords

Acute Altitude Illness

Altitude Illness

Altitude sickness

MeSH

Pulmonary edema of mountaineers

RPR Commentary

A summary of recommended measures to prevent and treat altitude sickness. James W. Mold, MD, MPH

Abstract

People traveling to high altitude are at risk of developing acute altitude illnesses, including AMS, HACE, and HAPE. Incidence and risk are assessed by history of acute altitude illness, sleeping elevation above sea level on day 1 of travel, and rate of ascent. AMS incidence can range from approximately 3% in persons traveling to 2000 m (6561 ft) to 25% to 40% at altitudes above 4300 m (14 107 ft), with symptoms varying from mild to marked.3 While rare, HACE and HAPE are potentially life-threatening if untreated.

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