University of Oklahoma Health Sciences Center

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Author/s:

Zou, Liye, Xiao, Tao, Cao, Chao, Smith, Lee, Imm, Kellie, Grabovac, Igor, Waldhoer, Thomas

Date Added:

September 22, 2020

Journal/Publication:

American Journal of Medicine

Publication Date:

September 15, 2020

URL:

Tai Chi for Chronic Illness Management: Synthesizing Current Evidence from Meta-Analyses of Randomized Controlled Trials

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1016/j.amjmed.2020.08.015.

Keywords

Tai Chi

chronic Illness

mind-body exercise

randomized controlled trial

umbrella review

RPR Commentary

Tai Chi appears to be helpful to people living with a variety of chronic illnesses. Not surprising since it is physical activity that nearly everyone can do to some degree with instruction. James W. Mold, MD, MPH

Abstract

An umbrella review of systematic reviews and meta-analyses of randomized controlled trials (RCTs) was conducted to evaluate the existing evidence of Tai Chi as a mind-body exercise for chronic illness management. MEDLINE/PubMed and Embase databases were searched from inception until 31st March 2019 for meta-analyses of at least two RCTs that investigated health outcomes associated with Tai Chi intervention. Evidence of significant outcomes (P-value <0.05) was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. This review identified 45 meta-analyses of RCTs and calculated 142 summary estimates among adults living with 16 types of chronic illnesses. Statistically significant results (P-value <0.05) were identified for 81 of the 142 outcomes (57.0%), of which 45 estimates presenting 30 unique outcomes across 14 chronic illnesses were supported by high (n=1) or moderate (n=44) evidence. Moderate evidence suggests that Tai Chi intervention improved physical functions and disease-specific outcomes compared with non-active controls and cardiorespiratory fitness compared with active controls among adults with diverse chronic illnesses. Between-study heterogeneity and publication bias were observed in some meta-analyses.

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