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University of Oklahoma Health Sciences Center

What Is Celiac Disease?

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Author/s: 
Kristin L. Walter
Date Added: 
August 17, 2026
Journal/Publication: 
JAMA Patient Page
Publisher: 
JAMA
Publication Date: 
August 12, 2026
Type: 
Patient Education Materials
Format: 
Article
DOI (1): 
10.1001/jama.2026.13079

RPR Commentary

Information for patients about celiac disease. James W. Mold, MD, MPH

Abstract

Celiac disease is a chronic autoimmune disease caused by consumption of gluten in people with specific genetic markers. Celiac disease affects about 1% of people worldwide and people can start having symptoms at any age. Individuals at increased risk include those with a first-degree relative who has celiac disease and those with autoimmune diseases (eg, type 1 diabetes or Hashimoto thyroiditis) and certain chromosomal conditions (Down syndrome, Turner syndrome, or Williams syndrome).

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