Objective. To assess selected adverse events of antidepressants in the treatment of major depressive disorder (MDD) in adults 65 years old or older. Antidepressants included in this review, as determined by expert opinion, are selective serotonin reuptake inhibitors (SSRIs),...
Library & Search Results
Adverse Effects of First-line Pharmacologic Treatments of Major Depression in Older Adults
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Terminating a Patient: Is It Time to Part Ways?
Many family physicians chose the specialty of family medicine because of the value placed on the therapeutic relationship between the patient and the physician. When that relationship is significantly or repeatedly challenged, family physicians feel it deeply, and it’s not always clear how best...
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Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review
BACKGROUND:
Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function...
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Concussion Incidence, Duration, and Return to School and Sport in 5- to 14-Year-Old American Football Athletes
OBJECTIVE:
To collect prospective data on concussion incidence, risk factors, duration of symptoms, and return to school and sport in 5- to 14-year-old American football participants.
STUDY DESIGN:
We conducted a prospective cohort study over 2 years collecting data during...
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Replacing sedentary time with physical activity: a 15-year follow-up of mortality in a national cohort
BACKGROUND:
Sedentary behavior is associated with health risks in adults. The potential benefits of reducing sedentary time may be dependent not only on decrease per se, but also on the type of activity it replaces. Few longitudinal studies have investigated the effects on mortality when...
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Effect of a Long Bout Versus Short Bouts of Walking on Weight Loss During a Weight‐Loss Diet: A Randomized Trial
OBJECTIVE:
This study aimed to evaluate the effect of different daily physical activity (PA) frequencies, while maintaining the same daily volume of PA, on weight loss, carbohydrate metabolism, and lipid metabolism in women with overweight or obesity throughout a 24-week intervention....
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Recommendations for Preventive Pediatric Health Care
American Academy of Pediatrics Preventative Care Priodicity Guideline.
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Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice
No abstract available.
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Quick Uptakes: Taking the Uncertainty Out of Interpreting BRCA Variants
The Problem
Testing for BRCA1 and BRCA2 mutations identifies both benign and pathogenic genetic variants. But information about specific variants, particularly those of uncertain clinical significance (VUS), often isn’t systematically curated, expertly reviewed, or...
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Pharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women: A Systematic Review and Network Meta-analysis of Clinical Outcomes
BACKGROUND:
Urinary incontinence (UI), a common malady in women, most often is classified as stress, urgency, or mixed.
PURPOSE:
To compare the effectiveness of pharmacologic and nonpharmacologic interventions to improve or cure stress, urgency, or mixed UI in nonpregnant ...
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