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The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application
Abstract
Background:
A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (...
Clinical guideline for homeless and vulnerably housed people, and people with lived homelessness experience
KEY POINTS
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Clinical assessment and care of homeless and vulnerably housed populations should include tailoring approaches to a person’s gender, age, Indigenous heritage, ethnicity and history of trauma; and advocacy for comprehensive primary health care.
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As...
Pharmacotherapy for the Treatment of Cannabis Use Disorder: A Systematic Review
BACKGROUND:
Cannabis use disorder (CUD) is a growing concern, and evidence-based data are needed to inform treatment options.
PURPOSE:
To review the benefits and risks of pharmacotherapies for the treatment of CUD.
DATA SOURCES:
MEDLINE, PsycINFO, Cochrane...
Ameliorative Effects Of N-Acetylcysteine As Adjunct Therapy On Symptoms Of Painful Diabetic Neuropathy
PURPOSE:
Painful diabetic neuropathy (PDN) is a variant of diabetic peripheral neuropathy which is highly prevalent and distressing in diabetic patients. Despite its high burden, the optimal treatment of PDN has remained a clinical challenge. To explain the emergence and maintenance of...
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Mental Health Conditions Among Patients Seeking and Undergoing Bariatric Surgery: A Meta-analysis
IMPORTANCE:
Bariatric surgery is associated with sustained weight loss and improved physical health status for severely obese individuals. Mental health conditions may be common among patients seeking bariatric surgery; however, the prevalence of these conditions and whether they are...
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Outcomes Associated With Oral Anticoagulants Plus Antiplatelets in Patients With Newly Diagnosed Atrial Fibrillation
IMPORTANCE:
Patients with nonvalvular atrial fibrillation at risk of stroke should receive oral anticoagulants (OAC). However, approximately 1 in 8 patients in the Global Anticoagulant Registry in the Field (GARFIELD-AF) registry are treated with antiplatelet (AP) drugs in addition to OAC...
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Preoperative Cardiac Risk Assessment
Major adverse cardiac events are common causes of perioperative mortality and major morbidity. Preventing these complications requires thorough preoperative risk assessment and postoperative monitoring of at-risk patients. Major guidelines recommend assessment based on a validated risk...
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Continuation of Annual Screening Mammography and Breast Cancer Mortality in Women Older Than 70 Years
BACKGROUND:
Randomized trials have shown that initiating breast cancer screening between ages 50 and 69 years and continuing it for 10 years decreases breast cancer mortality. However, no trials have studied whether or when women can safely stop screening mammography. An estimated 52% of ...
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