Importance: Acute low back pain (LBP) is highly prevalent, with a presumed favorable prognosis; however, once chronic, LBP becomes a disabling and expensive condition. Acute to chronic LBP transition rates vary widely owing to absence of standardized operational definitions, and...
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Risk Factors Associated With Transition From Acute to Chronic Low Back Pain in US Patients Seeking Primary Care
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Diagnosis and treatment of adenomyosis
Adenomyosis is a benign gynecological disorder characterized by aberrant development of endometrial glands and stroma within the myometrium, causing inflammation and neuroangiogenesis. Adenomyosis often coexists with other gynecological conditions and may cloud the clinical presentation.
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Screening for Asymptomatic Carotid Artery Stenosis US Preventive Services Task Force Recommendation Statement
Importance: Carotid artery stenosis is atherosclerotic disease that affects extracranial carotid arteries. Asymptomatic carotid artery stenosis refers to stenosis in persons without a history of ischemic stroke, transient ischemic attack, or other neurologic symptoms referable...
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Total knee replacement after high tibial osteotomy: time-to-event analysis and predictors
BACKGROUND: An important aim of high tibial osteotomy (HTO) is to prevent or delay the need for total knee replacement (TKR). We sought to estimate the frequency and timing of conversion from HTO to TKR and the factors associated with it.
METHODS: We...
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Conservative versus surgical management for patients with rotator cuff tears: a systematic review and META-analysis
Background: This study aims to compare conservative versus surgical management for patients with full-thickness RC tear in terms of clinical and structural outcomes at 1 and 2 years of follow-up.
Methods: A comprehensive search of CENTRAL, MEDLINE, EMBASE...
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Cancer Prevalence and Risk Stratification in Adults Presenting With Hematuria: A Population-Based Cohort Study
Abstract
Objective
To calculate the prevalence of renal cell carcinoma (RCC), upper urinary tract urothelial carcinoma (UT-UC), and lower urinary tract urothelial carcinoma (LT-UC) in patients with gross asymptomatic microhematuria (AMH) and symptomatic microhematuria (SMH).
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Allergic Reactions Including Anaphylaxis After Receipt of the First Dose of Pfizer-BioNTech COVID-19 Vaccine
On December 11, 2020, the US Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine, administered as 2 doses separated by 21 days....
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A Battery of Easily Accessible, Simple Tools for the Assessment of Concussion in Children
Objective: To determine whether a non-proprietary, novel testing battery can identify recently concussed children within 8 weeks of injury.
Study design: In total, 568 clinic outpatients aged 10-18 years were sorted into 3 groups: 316 had never been...
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Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons: US Preventive Services Task Force Recommendation Statement
Tobacco use is the leading preventable cause of disease, disability, and death in the US. In 2014, it was estimated that 480 000 deaths annually are attributed to cigarette smoking, including second hand smoke exposure. Smoking during pregnancy can increase the risk of numerous adverse pregnancy...
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Clinical Diagnosis of Benign Paroxysmal Positional Vertigo and Vestibular Neuritis
• Assess patients with vertigo for focal neurologic signs and symptoms, sustained substantial headache or neck pain, inability to stand and spontaneous vertical nystagmus.
• Perform the Dix–Hallpike test only for patients with episodes of vertigo less than 2 minutes and no nystagmus at...
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