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FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions

The U.S. Food and Drug Administration today is requiring safety labeling changes for a class of antibiotics called fluoroquinolones to strengthen the warnings about the risks of mental health side effects and serious blood sugar disturbances, and make these warnings more consistent across the...

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fluoroquinolones bronchitis sinusitis

Anticoagulant Comparison Chart

Author/s: North American Thrombosis Forum

After being diagnosed with a blood clot, navigating the different medications can be confusing. NATF has designed a chart comparing the different anticoagulant medications, which include warfarin and the direct oral anticoagulants (DOACs).

This is a great tool for patients to use when...

Keywords/Tags:
blood clot medication

Pharmacotherapy for Adults With Alcohol Use Disorder (AUD) in Outpatient Settings

Author/s: John M. Eisenberg Center for Clinical Decisions and Communications Science

Focus of This Summary

This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects of medications in adults with alcohol use disorder (AUD). The ...

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alcohol use disorder pharmacotherapy patient care

Final Recommendation Statement: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions

Importance

The USPSTF uses the term “unhealthy alcohol use” to define a spectrum of behaviors, from risky drinking to alcohol use disorder (AUD) (eg, harmful alcohol use, abuse, or dependence) (...

Management of Carpal Tunnel Syndrome Evidence-Based Clinical Practice Guideline

Author/s: American Academy of Orthopaedic Surgery

Overview

This clinical practice guideline is based on a systematic review of published studies with regard to the diagnosis and treatment of carpal tunnel syndrome (CTS). In addition to providing practice recommendations, this guideline also highlights limitations in the...

Keywords/Tags:
carpal tunnel syndrome diagnosis compression neuropathy median nerve

Drug Threat Bulletin: DSUVIA (Sufentanil)

Author/s: Oklahoma Bureau of Narcotics and Dangerous Drugs

The US Food and Drug Administration (FDA) approved DSUVIA, the synthetic opioid sufentanil in tiny blue tablet form, on Nov. 2, 2018 for single doses ingested under the tongue. Sufentanil is chemically similar to fentanyl (the lethal narcotic showing up as fake oxycodone pills and as a cutting...

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DSUVIA opioids opioid-use disorder sufentanil

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

Author/s: Hayden, Frederick G., Sugaya, Norio, Hirotsu, Nobuo, Lee, Nelson, de Jong, Menno D., Hurt, Aeron C., Ishida, Tadashi, Sekino, Hisakuni, Yamada, Kota, Portsmouth, Simon, Kawaguchi, Keiko, Shishido, Takao, Arai, Masatsugu, Tsuchiya, Kenji, Uehara, Takeki, Watanabe, Akira, Baloxavir Marboxil Investigators Group

BACKGROUND:

Baloxavir marboxil is a selective inhibitor of influenza cap-dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains resistant to current antiviral agents.

METHODS:

We conducted two...

Keywords/Tags:
baloxavir marboxil oseltamivir influenza

Pharmacologic Management of Newly Detected Atrial Fibrillation

Author/s: Frost, Jennifer L., Campos-Outcalt, Doug, Hoelting, David, LeFevre, Michael, Lin, Kenneth W., Vaughan, William, Bird, Melanie D.

Purpose
To review the evidence and provide clinical recommendations for the pharmacologic management of atrial fibrillation.
 

Methods
This guideline is based on two systematic reviews of published randomized controlled trials (RCTs) and...

Keywords/Tags:
atrial fibrillation pharmacologic management

Catheter Ablation of Atrial Fibrillation: An Overview for Clinicians

Author/s: Nebojša, Marinković, Milan, Lenarczyk, Radoslaw, Tilz, Roland, Potpara, Tatjana S.

Abstract

Catheter ablation (CA) of atrial fibrillation (AF) is currently one of the most commonly performed electrophysiology procedures. Ablation of paroxysmal AF is based on the elimination of triggers by pulmonary vein isolation (PVI), while different strategies for additional AF...

Keywords/Tags:
atrial fibrillation catheter ablation interventional cardiology pulmonary vein isolation stroke substrate modification

FRAMES: The Essentials of a Brief Intervention for Problem Drinking Pocket Cards

Pocket cards of FRAMES: brief intervention for problem drinkers.
Keywords/Tags:
alcoholism drinking interventions alcohol

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