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Recent Resources
Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
BACKGROUND:
Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of craving and withdrawal symptoms. Although there is clear evidence that NRT used after smoking ...
The effects of a home-based exercise intervention on elderly patients with knee osteoarthritis: a quasi-experimental study
BACKGROUND:
Knee osteoarthritis (KOA) is common in elderly people, causes pain, loss of physical functioning, and disability. This was a two-arm, superiority, quasi-experimental trial. The aim of this study was to evaluate the effectiveness of a home-based exercise intervention (HBEI) to...
Subclinical thyroid dysfunction is associated with adverse prognosis in heart failure patients with reduced ejection fraction
BACKGROUND:
Subclinical thyroid dysfunction whose typical patterns include subclinical hypothyroidism and subclinical hyperthyroidism, has been indicated to be associated with an increased risk of heart failure (HF). However, the relationship between subclinical thyroid dysfunction and...
Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review
Objective. To summarize the effects of long-term osteoporosis drug treatment (ODT) and ODT discontinuation and holidays on fractures and harms.
Data sources. MEDLINE®, Embase®, and Cochrane databases from 1995 to October 2018; ClinicalTrials.gov;...
Association of State Laws With Influenza Vaccination of Hospital Personnel
Introduction
Healthcare personnel influenza vaccination can reduce influenza illness and patient mortality. State laws are one tool promoting healthcare personnel influenza vaccination.
Methods
A 2016 legal assessment in 50 states and Washington DC identified (1) assessment...
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
BACKGROUND
Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve...
A Systematic Review of Trials to Improve Child Outcomes Associated With Adverse Childhood Experiences
Context
The purpose of this systematic literature review was to summarize current evidence from RCTs for the efficacy of interventions involving pediatric health care to prevent poor outcomes associated with adverse childhood experiences measured in childhood (C-ACEs).
Evidence...
Influence of changes in diet quality on unhealthy aging: the Seniors-ENRICA cohort
Background
Whether adopting a better diet in late life influences the aging process is still uncertain. Thus, we examined the association between changes in diet quality and unhealthy aging.
Methods
Data came from 2042 individuals aged ≥ 60 years recruited in the Seniors-...
Does CBD Actually Work?
Perhaps you’ve heard a lot of people are using CBD.
The chemical compound, naturally occurring in cannabis plants, doesn’t get you high, but does have a wide swath of other purported...