Summary
Background
Guideline-recommended doses of angiotensin-converting-enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs), and β blockers are similar for men and women with heart failure with reduced ejection fraction (HFrEF), even though there are known sex...
OBJECTIVES:
To test differences in cognitive outcomes among adolescents randomly assigned previously as infants to iron-fortified formulaor low-iron formula as part of an iron deficiency anemia prevention trial.
STUDY DESIGN:
Infants were recruited from community clinics in...
When it comes to living longer, reaching the oft-repeated goal of 10 000 steps per day may not be necessary. Older women who walked more than their peers had lower death rates in a recent observational ...
BACKGROUND
Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).
METHODS
We performed a multicenter, open-label,...
IMPORTANCE:
Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia.
OBJECTIVE:
To assess associations between anticholinergic drug treatments and risk of ...
Abstract
OBJECTIVE:
Disturbances in self-regulatory control are involved in the initiation and maintenance of addiction, including cannabis use disorder. In adults, long-term cannabis use is associated with disturbances in frontostriatal circuits during tasks that require the...
Abstract
OBJECTIVE:
To examine associations between gabapentinoids and adverse outcomes related to coordination disturbances (head or body injuries, or both and road traffic incidents or offences), mental health (suicidal behaviour, unintentional overdoses), and criminality.
...Spending time in natural environments can benefit health and well-being, but exposure-response relationships are under-researched. We examined associations between recreational nature contact in the last seven days and self-reported health and well-being. Participants (n = 19,806) were drawn...
Abstract
Purpose
To evaluate the consistency of 3 commonly used direct to consumer genetic testing kits.
Background
Genetic testing kits are widely marketed by several companies but the consistency of their results is unclear. Since identical twins share the same DNA...
BACKGROUND
We previously reported that a median of 5.6 years of intensive as compared with standard glucose lowering in 1791 military veterans with type 2 diabetes resulted in a risk of major cardiovascular events that was significantly lower (by 17%) after a total of 10 years of combined...
