Author/s: Kaul, Sanjay, Shah, S.A., Szeto, A.H., Farewell, Raechel, Shek, Allen, Fan, Dorothy, Quach, K.N., Bhattacharyya, Mouchumi, Elmiari, Jasmine, Chan, Winny, O'Dell, Kate, Nguyen, Nancy, McGaughey, T.J., Nasir, J.M.
Abstract
Background
Energy drinks have been linked to an increase in emergency room visits and deaths. We aim to determine the impact of energy drinks on electrocardiographic and hemodynamic parameters in young healthy volunteers.
Methods and Results
A randomized,...
Author/s: Mora, Samia, Chang, C. Lan, Moorthy, M. Vinayaga, Sever, Peter S.
IMPORTANCE:
Recent guidelines have recommended nonfasting for routine testing of lipid levels based on comparisons of nonfasting and fasting populations. However, no previous study has examined the association of cardiovascular outcomes with fasting vs nonfasting lipid levels measured in...
Author/s: Inge, Thomas H., Courcoulas, Anita P., Jenkins, Tod M., Michalsky, Marc P., Brandt, Mary L., Xanthakos, Stavra A., Dixon, John B., Harmon, Carroll M., Chen, Mike K., Xie, Changchun, Evans, Mary E., Helmrath, Michael A.
BACKGROUND
Bariatric surgery results in weight loss and health improvements in adults and adolescents. However, whether outcomes differ according to the age of the patient at the time of surgery is unclear.
METHODS
We evaluated the health effects of Roux-en-Y gastric bypass...
Author/s: Beasley, Richard, Holliday, Mark, Reddel, Helen K., Braithwaite, Irene, Ebmeier, Stefan, Hancox, Robert J., Harrison, Tim, Houghton, Claire, Oldfield, Karen, Papi, Alberto, Pavord, Ian D., Williams, Mathew, Weatherall, Mark
BACKGROUND:
In double-blind, placebo-controlled trials, budesonide-formoterol used on an as-needed basis resulted in a lower risk of severe exacerbation of asthma than as-needed use of a short-acting β2-agonist (SABA); the risk was similar to that of budesonide maintenance therapy plus as...
Author/s: Chen, Hongbo, Zheng, Xiaoyan, Huang, Hongjie, Liu, Congying, Wan, Qiaoqin, Shang, Shaomei
BACKGROUND:
Knee osteoarthritis (KOA) is common in elderly people, causes pain, loss of physical functioning, and disability. This was a two-arm, superiority, quasi-experimental trial. The aim of this study was to evaluate the effectiveness of a home-based exercise intervention (HBEI) to...
Author/s: Ortolá, Rosario, García-Esquinas, Esther, García-Varela, Giselle, Struijkab, Ellen A., Rodríguez-Artalejo, Fernando, Lopez-Garcia, Esther
Background
Whether adopting a better diet in late life influences the aging process is still uncertain. Thus, we examined the association between changes in diet quality and unhealthy aging.
Methods
Data came from 2042 individuals aged ≥ 60 years recruited in the Seniors-...
Author/s: Perkovic, Vlado, Jardine, Meg J., Neal, Bruce, Bompoint, Severine, Heerspink, Hiddo J. L., Charytan, David M., Edwards, Robert, Agarwal, Rajiv, Bakris, George, Bull, Scott, Cannon, Christopher P., Capuano, George, Chu, Pei-Ling, de Zeeuw, Dick, Greene, Tom, Levin, Adeera, Pollock, Carol, Wheeler, David C., Yavin, Yshai, Zhang, Hong, Zinman, Bernard, Meininger, Gary, Brenner, Barry M., Mahaffey, Kenneth W.
BACKGROUND
Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve...
Author/s: Leddy, John J., Haider, Mohammad N., Ellis, Michael J., Mannix, Rebekah, Darling, Scott R., Freitas, Michael S., Suffoletto, Heidi N., Leiter, Jeff, Cordingley, Dean M., Willer, Barry
IMPORTANCE:
Sport-related concussion (SRC) is a significant public health problem without an effective treatment.
OBJECTIVE:
To assess the effectiveness of subsymptom threshold aerobic exercise vs a placebo-like stretching program prescribed to adolescents in the acute phase...
Author/s: Chrisman, Sara P. D., Lowry, Sara, Herring, Stanley A., Kroshus, Emily, Hoopes, Teah R., Higgins, Shannon K., Rivara, Frederick P.
OBJECTIVE:
To collect prospective data on concussion incidence, risk factors, duration of symptoms, and return to school and sport in 5- to 14-year-old American football participants.
STUDY DESIGN:
We conducted a prospective cohort study over 2 years collecting data during...
Author/s: Dohrn, Ing-Mari, Kwak, Lydia, Oja, Pekka, Sjöström, Michael, Hagströmer, Maria
BACKGROUND:
Sedentary behavior is associated with health risks in adults. The potential benefits of reducing sedentary time may be dependent not only on decrease per se, but also on the type of activity it replaces. Few longitudinal studies have investigated the effects on mortality when...