Extensive research over the past half century has shown that curcumin (diferuloylmethane), a component of the golden spice turmeric (Curcuma longa), can modulate multiple cell signaling pathways. Extensive clinical trials over the past quarter century have addressed the pharmacokinetics, safety...
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Countering Vaccine Hesitancy
Immunizations have led to a significant decrease in rates of vaccine-preventable diseases and have made a significant impact on the health of children. However, some parents express concerns about vaccine safety and the necessity of vaccines. The concerns of parents range from hesitancy about...
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A Randomized Trial of Intensive versus Standard Blood-Pressure Control
BACKGROUND
The most appropriate targets for systolic blood pressure to reduce cardiovascular morbidity and mortality among persons without diabetes remain uncertain.
METHODS
We randomly assigned 9361 persons with a systolic blood pressure of 130 mm Hg or higher and an...
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Turmeric Dosage: How Much Should You Take Per Day?
You may know turmeric primarily as a spice, but it’s also used in Ayurvedic medicine, a holistic approach to health that originated in India over 3,000 years ago.
Turmeric supplements are now widely available for medicinal use, but knowing how much to take can be confusing.
Here’s...
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Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
BACKGROUND:
Randomised controlled trials (RCTs) exploring the potential of vitamin D to prevent acuterespiratory infections have yielded mixed results. Individual participant data (IPD) meta-analysis has the potential to identify factors that may explain this heterogeneity.
...
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Comparing Automated Office Blood Pressure Readings With Other Methods of Blood Pressure Measurement for Identifying Patients With Possible Hypertension: A Systematic Review and Meta-analysis
IMPORTANCE:
Automated office blood pressure (AOBP) measurement involves recording several blood pressure (BP) readings using a fully automated oscillometric sphygmomanometer with the patient resting alone in a quiet place. Although several studies have shown AOBP measurement to be more...
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Health Benefits of Smoking Cessation
There are immediate and long-term health benefits of quitting for all smokers.
Beneficial health changes that take place:
- Within 20 minutes, your heart rate and blood pressure drop.
- 12 hours, the carbon monoxide level in your blood drops to normal.
- 2-12...
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A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy
BACKGROUND
E-cigarettes are commonly used in attempts to stop smoking, but evidence is limited regarding their effectiveness as compared with that of nicotine products approved as smoking-cessation treatments.
METHODS
We randomly assigned adults attending U.K. National...
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Diagnosis and Management of Infectious Diarrhea
Infectious diarrhea is the fifth leading cause of death worldwide. In the United States, 179 million cases of acute diarrhea occur per year. Most diarrheal illnesses are self-limited and do not require evaluation or treatment beyond supportive care such as rehydration. Some infections do require...
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Parents' Guide to Childhood Immunizations
The CDC childhood immunizations frequently asked questions.
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