Background: Most patients with irritable bowel syndrome (IBS) are managed in primary care. When first-line therapies for IBS are ineffective, the UK National Institute for Health and Care Excellence guideline suggests considering low- dose tricyclic antidepressants as second-line treatment, but...
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Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review
Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review
Background. Unhealthy alcohol use is the third leading preventable cause of death in the United States, accounting for more than 140,000 deaths annually. Only 0.9 percent of Americans who...
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Topical Nonprescription Pain Medications for Adults
This JAMA Patient Page describes the types of topical nonprescription pain medications and tips for using them.
Topical nonprescription pain medications are over-the-counter drugs applied to the skin to treat pain.
Topical pain medications can effectively treat pain caused by...
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What Parents Should Know About Gun Safety in the Home and Vehicle
This Patient Page describes safety measures parents can take to protect children from gun violence.
Guns are now the leading cause of death for children in the US.
Guns are even more lethal than motor vehicle crashes. The reasons for this gun violence increase in children are...
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Effects of dance therapy on cognitive and mental health in adults aged 55 years and older with mild cognitive impairment: a systematic review and meta-analysis
Background: Individuals with mild cognitive impairment are at high risk of developing dementia. Dance therapy has promising applications in delaying cognitive decline. However, the effectiveness of dance therapy for older adults with mild cognitive impairment is unclear. The objective of this...
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Management of de Quervain Tenosynovitis: A Systematic Review and Network Meta-Analysis
Importance: There is a plethora of treatment options for patients with de Quervain tenosynovitis (DQT), but there are limited data on their effectiveness and no definitive management guidelines.
Objective: To assess and compare the effectiveness associated with available treatment options...
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Cervical Cancer Screening
This JAMA Patient Page discusses screening for cervical cancer, including who should be screened, recommendations for handling positive results, and the prevention of cervical cancer.
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Topical Therapies for Atopic Dermatitis
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting approximately 10% of the US population. AD often occurs as a childhood disease in conjunction with allergies and asthma, but it can also persist into or arise de novo in adulthood. AD negatively affects quality of life,...
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Evaluation and Treatment of Knee Pain: A Review
Importance: Approximately 5% of all primary care visits in adults are related to knee pain. Osteoarthritis (OA), patellofemoral pain, and meniscal tears are among the most common causes of knee pain.
Observations: Knee OA, affecting an estimated 654 million people worldwide, is the most...
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Hyperthyroidism: A Review
Importance: Overt hyperthyroidism, defined as suppressed thyrotropin (previously thyroid-stimulating hormone) and high concentration of triiodothyronine (T3) and/or free thyroxine (FT4), affects approximately 0.2% to 1.4% of people worldwide. Subclinical hyperthyroidism, defined as low...
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