University of Oklahoma Health Sciences Center

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Author/s:

Kerlikowske, Karla", C.M., Miglioretti, D.L.

Date Added:

June 4, 2019

Journal/Publication:

JAMA

Publisher:

JAMA Network

Publication Date:

May 31, 2019

URL:

Discussions of Dense Breasts, Breast Cancer Risk, and Screening Choices in 2019

Type:

Meta-analyses, Reviews, and Guidelines

Format:

Article

DOI (1):

10.1001/jama.2019.6247

Keywords

breast cancer

Breast

Radiologists

Radiology

mammography screening

mammography

MeSH

Breast Density

risk factors

Reproducibility of Results

mammography

Breast

breast neoplasms

early detection of cancer

Radiologists

Adipose Tissue

RPR Commentary

This is a concise review of what we know now about breast density and cancer risk and how to help patients interpret mammographic reports. James W. Mold, MD, MPH

Abstract

Breast density, a radiologic term that describes the proportion of parenchymal relative to fatty tissue in mammograms, is a strong and prevalent risk factor. With increasing breast density, the risk of having a breast cancer masked or hidden on mammography increases, as does future breast cancer risk.1 Almost 50% of US women aged 40 to 74 years have dense breasts (an estimated 27.6 million women). The widespread incorporation of breast density information into screening mammography reports in 36 US states and suggestion to consider supplemental imaging has resulted in women raising questions about breast density and supplemental imaging with their clinicians.2 Thus, clinicians need to be knowledgeable of the clinical significance of breast density and how it may be useful when combined with breast cancer risk to inform screening discussions.

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