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Bedbugs

Author/s: Freedman, A., McDougall, L., Lamy, P.

A resurgence in bedbugs is a result of increased travel and insecticide resistance
Many bedbug populations are resistant to pyrethroid, a chemical contained in most currently used insecticides.1 Bedbugs multiply exponentially, with thousands of bugs per infestation after 2–3 months.
Keywords/Tags:
bedbugs insecticide resistance bedbug bites antihistamines anxiety

Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes The GRADE Randomized Clinical Trial

Author/s: Wexler, D. J., de Boer, I. H., Ghosh, A., Younes, N., Bebu, I., Inzucchi, S. E., McGill, J. B., Mudaliar, S., Schade, D., Steffes, M., Tamborlane, W. V., Tan, M. H., Ismail-Beigi, F., GRADE Research Group

Importance: Type 2 diabetes (T2D) is the leading cause of kidney disease in the US. It is not known whether glucose-lowering medications differentially affect kidney function.

Objective: To evaluate kidney outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative...

Keywords/Tags:
Intention to Treat Analysis Albumins Creatinine diabetes, type 2 kidney function

A pragmatic approach to the management of menopause

Author/s: Lega, I. C., Fine, A., Antoniades, M. L., Jacobson, M.

Menopause is defined as 1 year of amenorrhea caused by
declining ovarian reserve or as the onset of vasomotor
symptoms in people with iatrogenic amenorrhea. It is preceded
by perimenopause or the menopause transition, which can last
for as long as 10 years. Although many...

Keywords/Tags:
quality of life menopause risk assessment fear Morbidity

Recommendations on screening for primary prevention of fragility fractures

Author/s: Thériault, G., Limburg, H., Klarenbach, S., Reynolds, D. L., Riva, J. J., Thombs, B. D., Tessier, L. A., Grad, R., Wilson, B. J., Canadian Task Force on Preventive Health Care

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task Force on Preventive Health Care (task force) guideline provides evidence-based recommendations on...

Keywords/Tags:
fractures fragility fractures aged risk assessment Canada

What Is Narcolepsy?

Author/s: Sum-Ping, O., Mignot, E.

Narcolepsy is a chronic disorder that causes excessive daytime sleepiness
and other symptoms that are due to abnormal rapid eye movement (REM) sleep.
Other signs and symptoms:
• Quick transitions into REM sleep
• Vivid dreams, hallucinations, and sleep paralysis
•...

Keywords/Tags:
Sleep Paralysis Narcolepsy Wakefulness Emotions Hallucinations

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment

Author/s: Byrne, P., Demasi, M., Jones, M.

Importance The association between statin-induced reduction in low-density lipoprotein cholesterol (LDL-C) levels and the absolute risk reduction of individual, rather than composite, outcomes, such as all-cause mortality, myocardial infarction, or stroke, is unclear.

Objective To...

Keywords/Tags:
adult cholesterol stroke prevention

Sleep as a vital sign

Author/s: Hirschtritt, M.E., Walker, M. P., Krystal, A.D.

Sleep is causally linked to the maintenance of every major physiological body system and disturbed sleep contributes to myriad diseases. The problem is, however, is that patients do not consistently, nor spontaneously, report sleep problems to their clinicians. Compounding the problem, there is...

Keywords/Tags:
sleep disrupted sleep sleep screenings

Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections

Author/s: Luetkemeyer, A. F., Donnell, D., Dombrowski, J. C., Cohen, S., Grabow, C., Brown, C. E., Malinski, C., Perkins, R., Nasser, M., Lopez, C., Vittinghoff, E., Buchbinder, S. P., Scott, H., Charlebois, E. D., Havlir, D. V., Soge, O. O., Celum, C., DoxyPEP Study Team

Background: Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed.

Methods: We conducted an open-label, randomized study involving MSM and transgender women who were taking preexposure prophylaxis (PrEP) against human...

Keywords/Tags:
sexually transmitted diseases sexual and gender minorities primary prevention HIV prevention doxycycline

Approach to atrial fibrillation: Essentials for primary care

Author/s: Bell, A., Andrade, J. G., Macle, L., Connelly, K. A., LaBine, L., Singer, A. G.

Objective: To support family physicians in preventing atrial fibrillation (AF) in patients at risk and in identifying and managing those with established AF; and to summarize key recommendations for ideal screening and care of patients.

Sources of information: The 2020 Canadian...

Keywords/Tags:
atrial fibrillation anticoagulants stroke prevention primary health care Chronic Disease

Lung cancer crash course

Author/s: Wilkinson, A. N.

Lung cancer has the highest mortality rate of any cancer in Canada, causing 25.5% of all cancer deaths, with a 5-year survival rate of only 19%. More than half of lung cancers are metastatic at diagnosis, with common sites of metastases in the brain, bone, liver, and adrenal glands. Lung cancer...

Keywords/Tags:
liver brain Survival Rate Small Cell Lung Carcinoma Canada

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