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2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy

Author/s: Joint Committee on Clinical Practice Guidelines

Not available. 
Keywords/Tags:
hypertension

Interventions for Breathlessness in Patients With Advanced Cancer

Author/s: Gupta, A., Waldfogel, J.M., Sharma, R., Feliciano, J.L., Sedhom, R., Day, J., Gersten, R.A., Davidson, P.M.

Main Points

For patients with advanced cancer:

  • Airflow interventions (fans) were more effective for improving breathlessness compared with usual care or sham.
  • Bilevel ventilation (a form of noninvasive positive pressure ventilation) was more effective than standard...

Efficacy and safety of lowering LDL cholesterol in older patients: a systematic review and meta-analysis of randomised controlled trials

Author/s: Gencer, Baris, Marston, Nicholas A., Im, KyungAh, Cannon, Christopher P., Sever, Peter, Keech, Anthony, Braunwald, Eugene, Giugliano, Robert P., Sabatine, Marc S.

Background: The clinical benefit of LDL cholesterol lowering treatment in older patients remains debated. We aimed to summarise the evidence of LDL cholesterol lowering therapies in older patients.

Methods: In this systematic review and meta-analysis, we...

Keywords/Tags:
Cardiovascular Diseases Clinical Protocols cholesterol

Effect of Vitamin D3 Supplements on Development of Advanced Cancer: A Secondary Analysis of the VITAL Randomized Clinical Trial

Author/s: Chandler, P.D., Chen, W.Y., Ojala, O.N.

Importance  Epidemiologic and trial data suggest that vitamin D supplementation may reduce metastatic cancer and cancer mortality, reflecting shared biological pathways.

Objective  To follow up on the possible reduction in cancer death in the Vitamin D...

Standards of Medical Care in Diabetes

Not available.

CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY

Author/s: Garber, A.J., Handelsman, Y., Grunberger, G., Einhorn, D., Abrahamson, M.J., Barzilay, J.I., Blonde, L., Bush, M.A.

No abstract available.

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

Author/s: Gregory A., Ovsyannikova , Inna G., Kennedy, Richard B.

Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such as hyperimmune globulin and convalescent human plasma, and to developing vaccines, antivirals, and monoclonal antibodies...

Keywords/Tags:
COVID-19 SARS-CoV-2 COVID-19 vaccine Immunity

Cancer-Specific Mortality, All-Cause Mortality, and Overdiagnosis in Lung Cancer Screening Trials: A Meta-Analysis

Author/s: Ebell, M.H., Bentivegna, M., Hulme, C.

Abstract

Purpose: Benefit of lung cancer screening using low-dose computed tomography (LDCT) in reducing lung cancer-specific and all-cause mortality is unclear. We undertook a meta-analysis to assess its associations with outcomes.

Methods: We...

Keywords/Tags:
cancer screening health services low-dose computed tomography lung cancer mass screening overdiagnosis preventive medicine public health

Diabetes Management in Chronic Kidney Disease: Synopsis of the 2020 KDIGO Clinical Practice Guideline

Author/s: Navaneethan, Sankar D., Zougas, Sophia, Caramori, M.L., Chan, Juliana C.N., Heerspink, Hiddo J.L., Hurst, Clint, Liew, Adrian, Michos, Erin D., Olowu, Wasiu A., Sadusky, Tami, Tandon, Nikhil, Tuttle, Katherine R., Wanner, Christoph, Wilkens, Katy G., Lytvyn, Lyubov, Craig, Jonathan C., Tunnicliffe, David J., Howell, Martin, Tonelli, Marcello, Cheung, Michael, Earley, Amy, Rossing, Peter, De Boer, Ian H., Khunti, Kamlesh

Description: The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed a clinical practice guideline in 2020 for the management of patients with diabetes and chronic kidney disease (CKD).

Methods: The KDIGO Work Group (WG) was tasked...

Keywords/Tags:
Medical dialysis clucose proteins renal diseases Hypoglycemics Treatment guidelines chronic kidney disease type 2 diabetes Kidneys

The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial

Author/s: Jamali, N., Adib-Hajbaghery, M., Soleimani, A.

Abstract

Background: Some studies have shown the effect of oral administration of curcumin on knee pain. However, limited studies are available on the effect of topical curcumin. This study aimed to investigate the effect of curcumin ointment on knee pain in older adults...

Keywords/Tags:
curcumin Knee pain elderly Ointment osteoarthritis

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