Long-term patient-reported outcomes are needed to inform treatment decisions for localized prostate cancer.
METHODS
Patient-reported outcomes of 1643 randomly assigned participants in the ProtecT (Prostate Testing for Cancer and Treatment) trial were evaluated to assess the...
When out with your children, it is important to protect them from sunrays on sunny and cloudy days. Every sunburn will increase a person’s risk of having skin cancer later in life. Practicing sun safety can prevent skin aging and cancer.
The sun makes 2 types of ultraviolet (UV) rays, UVA...
Importance: Intranasal corticosteroids (INCs) remain the first-line treatment of chronic rhinosinusitis (CRS) in both adults and children, despite the lack of evidence regarding their efficacy in the pediatric population. Similarly, their effect on the sinonasal microbiome has not been well...
Primary aldosteronism (PA) is common among patients with hypokalemia and hypertension. Patients with PA are at an increased risk of chronic disease if undiagnosed or untreated. Expert consensus recommends screening for PA in high-risk populations. Most antihypertensive medications can be...
An action plan for patients with sickle cell disease developed by the Uniformed Services University. James W. Mold, MD, MPH
Importance: Earlier egg and peanut introduction probably reduces risk of egg and peanut allergy, respectively, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction.
Objective: To investigate associations between timing of...
KEY POINTS
Most patients who report a penicillin allergy do not have a serious allergy.
Penicillin allergy delabelling enables patients to receive penicillin and β-lactam antibiotics when indicated.
A simple algorithm allows for stratification of allergy risk for patients....
Lead poisoning usually causes no immediate symptoms, but over time, lead causes damage to developing brains, so children exposed to lead (even at low levels) can have slowed growth and development and problems with learning, behavior, hearing, and speech that may be permanent. Adults with lead...
Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 million people worldwide. Patients with HFpEF are hospitalized approximately 1.4 times per year and have an...
Cancer screening tests are not perfect. Test results may suggest cancer when there is none (false-positive screen). They can also miss cancer even if it is present (false-negative screen). False-positive results can lead to emotional stress and more testing without improving health. Screening...
