Importance Type 1 diabetes is defined by hyperglycemia due to autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to insulin deficiency, and accounts for 5% to 10% of all cases of diabetes. Type 1 diabetes affects approximately 2 million people in the US and 8.4...
Recent Resources
Evidence-Based Footwear Recommendations for Older Adults: Enhancing Mobility, Comfort, and Fall Prevention
Background: Older adults often struggle to find footwear suitable for their clinical needs, thus affecting mobility, safety, and quality of life. Proper footwear is important due to fall risk, balance impairments, knee osteoarthritis (OA), hallux rigidus, plantar fasciitis, diabetic neuropathy,...
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AAP Releases Its Own Childhood and Adolescent Immunization Schedule
The AAP recommends vaccines to protect children against 18 diseases. The updated CDC schedule removed routine recommendations for hepatitis A and B, COVID-19, respiratory syncytial virus, rotavirus, influenza, and meningococcal disease, instead only recommending them for certain groups at high...
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Medications for essential tremor
Clinical question
How effective are β-blockers and other first-line agents for essential tremor?
Bottom line
Older, small randomized controlled trials (RCTs) show that propranolol reduces tremor severity (about 2 points more than placebo on 10- to 15-point scales) and leads to...
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Approach to mallet finger injury: Practical guide for Canadian primary care physicians
Objective: To provide primary care physicians with an evidence-based approach to recognizing and managing mallet finger injuries.
Sources of information: A literature search was conducted in PubMed and Google Scholar using relevant key words and subject headings. Recommendations were...
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Medications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose: A Review
Importance: Opioid use disorder (OUD) involves compulsive opioid use that causes substantial distress or impairment at work, school, or home. OUD, which is the third most prevalent substance use disorder worldwide, affected an estimated 3.7% of US adults (9 367 000) in 2022 and caused 53 774...
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Hypertension and alcohol: a cross-sectional study comparing PEth with AUDIT and AUDIT-C in primary care
Background: This cross-sectional study aimed to describe proportions of patients with indications of alcohol consumption using phosphatidylethanol (PEth), the Alcohol Use Disorders Identification Test (AUDIT), and its consumption-focused version (AUDIT-C), in relation to blood pressure (BP)...
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Risk Factors for the Development of Food Allergy in Infants and Children: A Systematic Review and Meta-Analysis
Importance: The incidence and risk (predictive) factors for early life food allergy development remain uncertain.
Objective: To estimate the incidence and quantify risk factors for food allergy development.
Data sources: MEDLINE and Embase were systematically searched to January 1...
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The association between medication use and vitamin B12 deficiency in the elderly population: a cross- sectional study
Background
Vitamin B12 deficiency is common in the elderly population and can cause severe complications. The use of certain medication has in previous studies been associated with vitamin B12 deficiency in the general population. To identify elderly patients at risk for vitamin B12...
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Management of Premenstrual Disorders
Premenstrual disorders encompass a spectrum of cyclic affective and physical symptoms that interfere with daily functioning, occurring during the luteal phase and resolving with or immediately following menstruation. Premenstrual disorders may be caused by fluctuations of estrogen in the luteal...
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