Author/s: Rajesh T Gandhi, Raphael J Landovitz, Paul E Sax, Davey M Smith
Importance: New data and new antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection.
Objective: To provide updated recommendations for HIV treatment and clinical management and HIV prevention.
Methods: A panel of...
Author/s: Rebecca Voelker
This JAMA Patient Page describes genital herpes and its symptoms, diagnosis, treatment, and prevention measures.
Author/s: Hussain S Lalani, Catherine S Hwang, Aaron S Kesselheim, Benjamin N Rome
Importance In the US, many patients struggle to afford prescription drugs, leading to adverse health outcomes. To improve cost-related medication nonadherence, prescribers and clinical staff must understand how to assist patients in overcoming high prescription drug costs.
Observations...
The 2025 Immunization Schedules approved by ACIP and adopted by the CDC Director on October 24, 2024 are now available below.
Author/s: Barbara H Chaiyachati, Rachel E Linstead, Lindsay A Thompson
This JAMA Pediatrics Patient Page describes naloxone, a medication that reverses opioid poisoning or overdose.
Author/s: Douglas Tremblay, Marina Kremyanskaya, John Mascarenhas, Ronald Hoffman
Importance: Polycythemia vera (PV), a myeloproliferative neoplasm characterized by an increased red blood cell mass and increased risk of thrombosis, affects approximately 65 000 people in the US, with an annual incidence of 0.5 to 4.0 cases per 100 000 persons.
Observations:...
Author/s: Francis J Alenghat, Jason T Alexander, Gaurav A Upadhyay
Atrial fibrillation has a lifetime prevalence of 15% to 40% and predisposes patients to stroke and cardiac dysfunction. This JAMA Clinical Guidelines Synopsis focuses on recommendations for long-term management of AF, including new paradigms for rhythm control and stroke risk reduction.
Author/s: Jennifer E Flythe, Suzanne Watnick
Importance: More than 3.5 million people worldwide and 540 000 individuals in the US receive maintenance hemodialysis or peritoneal dialysis for the treatment of chronic kidney failure. The 5-year survival rate is approximately 40% after initiation of maintenance dialysis.
Observations:...
Author/s: Catherine M Otto, David E Newby, Graham S Hillis
Importance: Calcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65 years and approximately 12% of adults older...
The American Society of Addiction Medicine (ASAM) developed this National Practice Guideline for the Treatment of Opioid Use Disorder to provide information on evidence-based treatment of opioid use disorder. This guideline is an update and replacement of the 2015 ASAM National Practice...