Importance Globally, 968 350 new cases and 659 853 deaths from gastric cancer were reported in 2022. In the US, 30 300 new cases and 10 780 deaths were estimated in 2025.
Observations Gastric cancer is more common in men, and the median age at diagnosis is 68 years. Most gastric cancers...
Cervical cancer screening is one of the most significant public health accomplishments of the 20th century. Over the last 50 years, incidence and mortality rates from cervical cancer in the US have decreased by more than 50%1 because of widespread use of the Papanicolaou test and later adoption...
Half of all children have sleep issues at some point during childhood.
When a child does not sleep well, the entire family feels the impact. Sleep supports growth and development and prevents other illnesses. Poor sleep can lead to daytime irritability, trouble focusing, behavioral issues...
Importance Tai chi is a type of exercise recommended for knee osteoarthritis, but access to in-person tai chi can be limited.
Objective To evaluate the effects of an unsupervised multimodal online tai chi intervention on knee pain and function for people with knee osteoarthritis.
...Globally, the prevalence of chronic kidney disease is estimated to be approximately 850 million cases, with approximately 4 million individuals needing kidney replacement therapy for kidney failure. By 2050, chronic kidney disease is projected to become the fifth leading underlying cause of...
Measles is a highly contagious virus with a primary case reproduction number (i.e., the average number of secondary cases per case patient) of 12 to 18. It is currently spreading rapidly owing to reduced measles vaccination coverage, which is due primarily to the disruption of local immunization...
Hypothyroidism is a disease of thyroid hormone deficiency.
The most common cause of hypothyroidism worldwide is insufficient intake of iodine, a mineral found in iodized salt and some foods (such as seafood and dairy) that is needed for production of thyroid hormones. In the US and other...
Electronic health record (EHR)–based patient portals have enabled asynchronous communication between patients and physicians1,2 but have contributed to fragmented and inefficient work and subsequent physician burnout.3,4 In response, a large ambulatory network in the Western US set aside 1...
Allergic rhinitis affects approximately 1 in 6 adults, and chronic rhinosinusitis (CRS) affects approximately 1 in 8 adults in the US.1,2 Climate change, due in part to rising global temperatures secondary to release of carbon dioxide (CO2) and other greenhouse gases, is a growing public health...
Context
Current guidelines recommend indefinite anticoagulation after ablation of atrial fibrillation (AF) in patients with a CHA2DS2-VASc score ≥2–3, but few data support this practice. In a recent randomized trial (ALONE-AF), stopping anticoagulation 1 year after ablation did not raise...
