Author/s: Prashant Singh, Allen Lee, Neil M Sheth, William D Chey
Chronic diarrhea is defined as loose or watery stools lasting longer than 4 weeks and affects approximately 6% to 7% of adults in the US. More than 90% of patients with chronic diarrhea have a noninfectious etiology.
Observations The most common causes of chronic, noninfectious diarrhea...
Author/s: Benjamin Drum, Bryce La Course, Mark Kelly
Importance Accurate assessment of intravascular volume facilitates management decisions about fluid management in patients with volume overload.
Objective To identify the most accurate clinical examination, radiographic, and laboratory findings for assessing volume overload in...
Author/s: David Moloney, Ayman Youssef, Luis E. Okamoto
Importance: Orthostatic hypotension is a common but underrecognized condition that increases with age and is associated with a lower quality of life, falls, and increased mortality. The frequent coexistence of supine hypertension and postprandial hypotension with orthostatic hypotension makes it...
Author/s: Joseph A. Murray, Steffen Husby
Celiac disease, a common autoimmune condition affecting approximately 1% of the population, can develop with exposure to gluten at any age. Diagnosis involves serologic testing, especially for IgA antibodies against tissue transglutaminase, and may include tests to confirm the presence of...
Author/s: Alan H. Daniels, Daniel Alsoof, Sarah Criddle, Eren O. Kuris, Bryce Basques, Bassel G. Diebo
Low back pain is one of the most common causes of health care visits and has the highest global prevalence of all musculoskeletal conditions. Although musculoskeletal back pain is often temporary and self-limited, it may represent more worrisome pathologic conditions that can lead to permanent...
Author/s: Kareem Jamani, Ashley Chopek, Rajat Kumar, Gregory M.T. Guilcher
Sickle cell disease (SCD) is associated with major morbidity, reduced life expectancy, and impaired quality of life.
Transformative therapies for SCD include allogeneic hematopoietic stem cell transplant and gene therapy.
After successful transformative therapy, people with SCD no...
Author/s: Roger S. Blumenthal, Pamela B. Morris, Mario Gaudino, Heather M. Johnson, Timothy S. Anderson, Vera A. Bittner, Ron Blankstein, LaPrincess C. Brewer, Leslie Cho, Sarah D. de Ferranti, Eugenia Gianos, Ty J. Gluckman, Kristen F. Gradney, Ijeoma Isiadinso, Donald M. Lloyd-Jones, Joel C. Marrs, Seth S. Martin, Kellie H. McLain, Laxmi S. Mehta, Samia Mora, Wudeneh M. Mulugeta, Pradeep Natarajan, Ann Marie Navar, Carl E. Orringer, Tamar S. Polonsky, Harmony R. Reynolds, Joseph J. Saseen, Michael D. Shapiro, Daniel E. Soffer, Sheila A. Tynes, Chloé D. Villavaso, Salim S. Virani, John T. Wilkins
Aim: The "2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia" retires and replaces the "2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol."
Methods: A comprehensive literature...
Author/s: Michel Azizi, Wanpen Vongpatanasin, Naomi D L Fisher, Felix Mahfoud, Laurence Amar, Ajay J Kirtane
Importance: Hypertension, defined as office systolic blood pressure (SBP) 130 mm Hg or greater and/or diastolic blood pressure 80 mm Hg or greater, affects 43.9% of women and 49.5% of men in the US. Approximately 19.7% of patients treated for hypertension have apparent resistant hypertension (...
Author/s: Amber E Johnson, Christopher D Jackson, Jason T Alexander
Hypertension is the leading modifiable risk factor worldwide for ASCVD, and approximately half of US adults have hypertension.1 Uncontrolled BP contributes to heart failure, stroke, atrial fibrillation, and sudden cardiac death and is associated with development of kidney failure and dementia.2...
Author/s: Hannah C. Matthews, Jason T. Alexander
Guideline title ACG Clinical Guideline: Treatment of Helicobacter pylori Infection
Release date September 2024
Prior version 2017
Developer American College of Gastroenterology (ACG)
Target population Outpatients aged 18 years or older with H pylori infection, with...