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Recent Resources

Management of Systolic BP in the Elderly

Author/s: Mold, James

 Discuss management of blood pressure in the elderly:

§ Disease or risk factor

§ BP components and their significance

§ Benefits and hazards of BP reduction

§ Other ways to reduce CV risk and law of diminishing returns

§ BP...

Keywords/Tags:
hypertension elderly patients

Noninvasive Nonpharmacological Treatment for Chronic Pain: Evidence Summary

Author/s: Skelly, Andrea C., Chou, Roger, Dettori, Joseph R., Turner, Judith A., Friedly, Janna L., Rundell, Sean D., Fu, Rongwei, Brodt, Erika D., Wasson, Ngoc, Winter, Cassandra, Ferguson, Aaron J. R.

Purpose of Review

To assess which noninvasive nonpharmacological treatments for common chronic pain conditions improve function and pain for at least 1 month after treatment.

Key Messages

• Interventions that improved function and/ or pain for at least 1 month when used for...

Keywords/Tags:
chronic pain

Gabapentin for Chronic Neuropathic Pain in Adults

Author/s: Wiffen, Phillip J., Derry, Sheena, Bell, Rae F., Rice, Andrew S.C., Tölle, Thomas Rudolf, Phillips, Tudor, Moore, R. Andrew

BACKGROUND:

Gabapentin is commonly used to treat neuropathic pain (pain due to nerve damage). This review updates a review published in 2014, and previous reviews published in 2011, 2005 and 2000.

OBJECTIVES:

To assess the analgesic efficacy and adverse effects of gabapentin...

Keywords/Tags:
neuralgia neuropathic pain gabapentin

Amitriptyline for Neuropathic Pain in Adults

Author/s: Moore, R. Andrew, Derry, Sheena, Aldington, Dominic, Cole, Peter, Wiffen, Phillip J.

BACKGROUND:

This is an updated version of the original Cochrane review published in Issue 12, 2012. That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with in a separate review.Amitriptyline is a tricyclic...

Keywords/Tags:
Fibromyalgia amitriptyline neuropathic pain neuralgia

Short- and Long-Term Outcomes after Bariatric Surgery in the Medicare Population

Author/s: Orestis, A. Panagiotou, Markozannes, Georgios, Kowalski, Rishi, Di, Mengyang, Bond, Dale S., Ryder, Beth A., Adam, Gaelen P., Trikalinos, Thomas A.

Introduction. We conducted a technology assessment to summarize and appraise the current evidence regarding the effectiveness and safety of bariatric surgery in the Medicare-eligible population.

Data Sources. We searched six bibliographic databases and...

Keywords/Tags:
medicare gastric bypass weight loss bariatric surgery

Effects of Aspirin on Risks of Vascular Events and Cancer According to Bodyweight and Dose: Analysis of Individual Patient Data from Randomised Trials

Author/s: Rothwell, Peter M., Cook, Nancy R., Gaziano, J. Michael, Price, Jacqueline F., Blech, Jill F. F., Roncaglioni, Maria Carla, Morimoto, Takeshi, Mehta, Ziyah

BACKGROUND:

A one-dose-fits-all approach to use of aspirin has yielded only modest benefits in long-term prevention of cardiovascular events, possibly due to underdosing in patients of large body size and excess dosing in patients of small body size, which might also affect other outcomes...

Keywords/Tags:
aspirin cardiovascular events cancer

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Author/s: GBD 2016 Alcohol Collaborators

Background

Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the...

Keywords/Tags:
alcohol use risk-relations

Featured Review: Vertebroplasty for treating spinal fractures due to osteoporosis

Author/s: Buchbinder, Rachelle, Johnston, Renea V., Rischin, Kobi J., Jomik, Joanne, Jones, C. Allyson, Golmohammadi, Kamran, Kallmes, David F.

High quality evidence shows that vertebroplasty does not provide more clinically important benefits than placebo but may cause people harm.
Keywords/Tags:
vertebroplasty osteoporosis spine

Omega-6 fats for the primary and secondary prevention of cardiovascular disease

Author/s: Hooper, Lee, Al-Khudairy, Lena, Abdelhamid, Asmaa S., Rees, Karen, Brainard, Julii S., Brown, Tracey J., Ajabnoor, Sarah M., O'Brien, Alex T., Winstanley, Lauren E., Donaldson, Daisy H., Song, Fujian, Deane, Katherine H. O.

BACKGROUND:

Omega-6 fats are polyunsaturated fats vital for many physiological functions, but their effect on cardiovascular disease (CVD) risk is debated.

OBJECTIVES:

To assess effects of increasing omega-6 fats (linoleic acid (LA), gamma-linolenic acid (GLA), dihomo-gamma-...

Keywords/Tags:
omega-6 fatty acids cardiovascular disease

Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update

Author/s: Forman-Hoffman, Valerie, Middleton, Jennifer Cook, Feltner, Cynthia, Gaynes, Bradley N., Weber, Rachel Palmieri, Bann, Carla, Viswanathan, Meera, Lohr, Kathleen N., Baker, Claire, Green, Joshua

Objective. To assess efficacy, comparative effectiveness, and harms of psychological and pharmacological treatments for adults with posttraumatic stress disorder (PTSD) and to update the original 2013 review.

Data sources. MEDLINE®, CINAHL®, Cochrane...

Keywords/Tags:
PTSD therapy

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