Author/s: Wilding, John P.H., Batterham, Rachel L., Calanna, Salvatore, Davies, Melanie, Van Gaal, Luc F., Lingvay, Ildiko, McGowan, Barbara M., Rosenstock, Julio, Tran, Marie T.D., Wadden, Thomas A.,, Sean, Yokote, Koutaro, Zeuthen, Niels, Kushner, Robert F., STEP 1 Study Group
Background: Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed.
Methods: ...
Author/s: Primary Care First
Primary Care First is a voluntary five-year payment model that rewards value and quality by offering an innovative payment structure to support advanced primary care delivery. Primary Care First aims to improve quality and access to care for all patients, particularly those with complex chronic...
The 46th Annual Advances in Pediatrics is a one-day course for community Pediatricians provides an update of what is currently known about COVID-19 in the pediatric patient population both nationally and locally. The course is taught by 17 national and local experts. Each lecture based, active...
Author/s: Mendelson, Scott J., Prabhakaran, Shyam
Importance: Stroke is the fifth leading cause of death and a leading cause of disability in the United States, affecting nearly 800 000 individuals annually.
Observations: Sudden neurologic dysfunction caused by focal brain ischemia with imaging evidence...
Author/s: Miller, Benjamin F., Coffey, M. J.
KEY POINTS:
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Suicide rates have been rising during the past several years, but suicide is preventable.
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There are many known risk factors for suicide, but the predictive utility of any single risk factor is low, requiring a focus on population-level rather than...
Author/s: Whittaker, Robyn, McRobbie, Hayden, Bullen, Chris, Rodgers, Anthony, Gu, Yulong, Dobson, Rosie
Background: Mobile phone-based smoking cessation support (mCessation) offers the opportunity to provide behavioural support to those who cannot or do not want face-to-face support. In addition, mCessation can be automated and therefore provided affordably even in resource-poor...
Author/s: Sun, Dongmei, Phua, Chai W.
About 11% of patients in primary care reported bleeding symptoms in a 2010 Canadian study.1 Mild bleeding disorders should be considered in patients with disproportionate bleeding (i.e., excessive postsurgical bleeding...
Author/s: Alemi, Farrokh, Avramovic, Sanja, Schwartz, Mark D.
Existing methods of screening for substance abuse (standardized questionnaires or clinician's simply asking) have proven difficult to initiate and maintain in primary care settings. This article reports on how predictive modeling can be used to screen for substance abuse using extant data in...
Author/s: Winn, Aaron N., Check, Devon K., Farkas, Amy, Fergestrom, Nicole M., Neuner, Joan M., Roberts, Andrew W.
Importance: National efforts to improve safe opioid prescribing focus on preventing misuse, overdose, and opioid use disorder. This approach overlooks opportunities to better prevent other serious opioid-related harms in complex populations, such as older adult survivors of...
Author/s: Jalali, Mohammad S., Botticelli, Michael, Hwang, Rachael C., Koh, Howard K., McHugh, R. Kathryn
The prevalence of opioid use and misuse has provoked a staggering number of deaths over the past two and a half decades. Much attention has focused on individual risks according to various characteristics and experiences. However, broader social and contextual domains are also essential...