The Advisory Committee on Immunization Practices to the US Centers for Disease Control and Prevention provides annual recommendations for routine adult immunizations. Many recommendations consider patient factors such as age, medical conditions, and medications that increase an individual’s risk...
Recent Resources
COVID-19 Update From China
By mid-February 2020 there were 60,000 confirmed cases of COVID-19, the vast majority diagnosed in Hubei Province (including Wuhan city) in mainland China. China CDC Chief Epidemiologist Zunyou Wu, MD, PhD discusses the latest COVID-19 developments in the country with JAMA Editor in Chief Howard...
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
BACKGROUND:
In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia.
METHODS:
In this retrospective, single-centre study...
Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage
OBJECTIVE:
To compare the efficacy of zinc acetate lozenges with zinc gluconate lozenges in common cold treatment and to examine the dose-dependency of the effect.
DESIGN:
Meta-analysis.
SETTING:
Placebo-controlled zinc lozenge trials, in which the zinc dose...
Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality
Importance Subclinical hypothyroidism is a common clinical entity among US adults associated in some studies with an increase in the risk of cardiovascular disease (CVD) and mortality. However, the extent to which CVD mediates the association between elevated serum thyrotropin...
Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder
IMPORTANCE:
Although clinical trials demonstrate the superior effectiveness of medication for opioid use disorder (MOUD) compared with nonpharmacologic treatment, national data on the comparative effectiveness of real-world treatment pathways are lacking.
OBJECTIVE:
To...
Will Discontinuing the Use of Gabapentin Cause Withdrawal Symptoms?
Gabapentin is an anticonvulsant drug prescribed for seizures and nerve pain. People who develop physical dependence to gabapentin may experience withdrawal symptoms when they try to come off it. These symptoms can begin within 12 hours to 7 days after quitting the medication and last up to 10...
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