Author/s: Kevin Liang, Philip Hui, Samantha Green
Postinfectious cough affects 11%–25% of adults after a respiratory infection
Postinfectious cough is defined as a subacute cough, with symptoms lasting between 3 and 8 weeks.1 The preceding infection triggers an inflammatory cascade, increasing bronchial sensitivity and mucus production,...
Author/s: Laura Boucai, Mark Zafereo, Maria E Cabanillas
Importance: Approximately 43 720 new cases of thyroid carcinoma are expected to be diagnosed in 2023 in the US. Five-year relative survival is approximately 98.5%. This review summarizes current evidence regarding pathophysiology, diagnosis, and management of early-stage and advanced thyroid...
Author/s: Ebernella Shirin Dason, Olexandra Koshkina, Crystal Chan, Mara Sobel
KEY POINTS
Polycystic ovarian syndrome (PCOS) is a chronic disorder associated with infertility; miscarriage; adverse pregnancy outcomes; and cardiovascular, metabolic, psychological and neoplastic risks.
DIagnosis of PCOS can be made based on the presence of any 2 of menstrual...
Author/s: Mark H Ebell, Henry C Barry, Kanishka Baduni, Gabrielle Grasso
Purpose: We conducted a meta-analysis to evaluate clinically meaningful benefits and harms of monoclonal antibodies targeting amyloid in patients with Alzheimer dementia.
Methods: We searched PubMed, Cochrane CENTRAL, and 5 trial registries, as well as the reference lists of identified...
Author/s: Darren E R Warburton, Crystal Whitney Nicol, Shannon S D Bredin
The primary purpose of this narrative review was to evaluate the current literature and to provide further insight into the role physical inactivity plays in the development of chronic disease and premature death. We confirm that there is irrefutable evidence of the effectiveness of regular...
Author/s: Christopher J Humphreys, Ran R Liu, Taryn M Simms
Author/s: Katherine M Marsh, Felicia Scott-Wellington
Children, particularly adolescents, are dying from firearm-related injuries. Screening for firearms, early recognition of firearm-related concerns, appropriate referrals, and follow-up are crucial to the safety of our patients and their families. Clinicians are strongly encouraged to address...
Author/s: Manish H Dama, Ryan J Van Lieshout
Introduction: Existing guidelines for primary care clinicians (PCCs) on the detection and management of perinatal depression (PD) contain important gaps. This review aims to provide PCCs with a summary of clinically relevant evidence in the field.
Methods: A narrative literature review...
Author/s: Daniele Focosi, David J. Sullivan, Daniel F. Hanley, Mario Cruciani, Massimo Franchini, Jiangda Ou, Arturo Casadevall, Nigel Paneth
This COVID-19 outpatient randomized controlled trials (RCTs) systematic review compares hospitalization outcomes amongst four treatment classes over pandemic period, geography, variants, and vaccine status. Outpatient RCTs with hospitalization endpoint were identified in Pubmed searches through...
Author/s: Alvar Agustí, Antoni Sisó-Almirall, Miguel Roman, Claus F. Vogelmeier
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has issued its 2023 annual report1. Compared with former versions, it has been significantly updated. Here, we summarize the most relevant changes for a Primary Care audience. The complete document can be downloaded for free from...