Objectives. Attention deficit hyperactivity disorder (ADHD) is a common pediatric neurobehavioral disorder often treated in the primary care setting. This systematic review updates and extends two previous Agency for Healthcare Research and Quality (AHRQ) systematic evidence...
Library & Search Results
Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents Comparative Effectiveness Review No. 203
Bisphosphonates for Postmenopausal Osteoporosis
Bisphosphonates are the first-line pharmacologic treatment for postmenopausal osteoporosis and the most commonly prescribed medication for this condition.1 Bisphosphonates, classified as antiresorptive agents,...
Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD: A Systematic Review
Objectives. To synthesize existing knowledge about the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease (ECOPD).
Data sources. Embase®, Epub Ahead of Print, In-Process...
Primary Prevention of Cardiovascular Disease
Atherosclerotic CVD remains the leading cause of death for people of most racial/ethnic groups. In 2010, the AHA suggested metrics of ideal cardiovascular health in 7 domains (blood pressure, physical activity, cholesterol, diet, weight, smoking, and blood glucose). There have since been...
Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium
DESCRIPTION:
Dietary guideline recommendations require consideration of the certainty in the evidence, the magnitude of potential benefits and harms, and explicit consideration of people's values and preferences. A set of recommendations on red meat and processed meat consumption was...
Association between vitamin D supplementation and mortality: systematic review and meta-analysis
Abstract
OBJECTIVE:
To investigate whether vitamin D supplementation is associated with lower mortality in adults.
DESIGN:
Systematic review and meta-analysis of randomised controlled trials.
DATA SOURCES:
Medline, Embase, and the Cochrane Central...
Clinical Approach to Lactose Intolerance
Lactose intolerance refers to the clinical syndrome in which symptoms of bloating, flatulence, abdominal discomfort, and diarrhea arise following the consumption of lactose-containing foods. Lactose malabsorption results from congenital lactase deficiency, secondary lactose intolerance, and,...
An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease
Educational Objective
To understand how to diagnose and treat venous thromboembolic disease.
Venous thromboembolic disease is common. There are many steps necessary to establish a diagnosis or treat this disease. These are summarized in this JAMA Clinical...
Glucocorticoids for croup in children
BACKGROUND:
Glucocorticoids are commonly used for croup in children. This is an update of a Cochrane Review published in 1999 and previously updated in 2004 and 2011.
OBJECTIVES:
To examine the effects of glucocorticoids for the treatment of croup in children aged 0 to 18...
Medication-Assisted Treatment for Opioid-Use Disorder
The United States is in the midst of a national opioid epidemic. Physicians are encouraged both to prevent and treat opioid-use disorders (OUDs). Although there are 3 Food and Drug Administration-approved medications to treat OUD (methadone, buprenorphine, and naltrexone) and there is ample...