Importance Male hypogonadism is a clinical syndrome of signs and symptoms of testosterone deficiency and consistently low morning serum testosterone concentrations. The prevalence of hypogonadism due to hypothalamus, pituitary, or testes pathology is less than 1%, and the prevalence due to...
Recent Resources
Hearing Aids for Adults With Mild to Moderate Hearing Loss
Hearing loss is defined as an impaired ability to hear sounds at thresholds considered to be normal. Projections based on audiometric data from the National Health and Nutrition Examination Survey estimate that by 2030, approximately 55 million US adults will have hearing loss, including 35...
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Approach to Fatigue in Primary Care: A Practical Diagnostic Framework for General Practitioners
Fatigue is one of the most common presenting complaints in primary care and poses a significant diagnostic challenge due to its multifactorial aetiology. While the majority of cases are benign and self-limiting, fatigue may also represent an early manifestation of serious underlying pathology....
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Tramadol versus placebo for chronic pain: a systematic review with meta-analysis and trial sequential analysis
Objectives The objective of our study was to assess the benefits and harms of tramadol vs placebo in adults with chronic pain.
Design The research method was a systematic review of randomised clinical trials with meta-analysis. The review followed the Trial Sequential Analysis and the...
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Autism-Understanding Diagnosis, Prevalence, and Treatment: A Healthy Dialogue With Jeremy Veenstra-VanderWeele and Dost Öngür
Autism spectrum disorder (ASD) remains a topic of intense public interest, with debates over rising diagnosis rates, questions about causes, and new developments in treatments and outcomes. In the first episode of Healthy Dialogue, a new podcast from the JAMA Network, I sit down with JAMA...
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Hepatitis B: A Review
Importance: Hepatitis B virus (HBV) infection affects an estimated 254 million people worldwide and causes approximately 1.1 million deaths annually. In 2022, there were approximately 1.2 million new HBV infections worldwide and 14 000 in the US.
Observations: HBV is a DNA virus...
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Treatment of Anxiety for Adults in Primary Care Settings: A Review
Importance Anxiety disorders and symptoms are prevalent and burdensome, and patients are most likely to seek treatment in primary care settings. However, anxiety is underdetected and undertreated. This narrative review details behavioral and pharmacological treatment options that are feasible...
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I’m Concerned About Anxiety—What Do I Need to Know?
What Is Anxiety?
Anxiety is a normal experience of worry or fear about something the body or mind interprets as threatening. Anxiety may show up in your thoughts, emotions, body sensations, or behaviors (like worrying, feeling nervous, sweaty palms, and avoiding certain situations).
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I’m Concerned About Anxiety—What Do I Need to Know?
What Is Anxiety?
Anxiety is a normal experience of worry or fear about something the body or mind interprets as threatening. Anxiety may show up in your thoughts, emotions, body sensations, or behaviors (like worrying, feeling nervous, sweaty palms, and avoiding certain situations).
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Diagnosis and Management of Resistant Hypertension: A Review
Importance: Hypertension, defined as office systolic blood pressure (SBP) 130 mm Hg or greater and/or diastolic blood pressure 80 mm Hg or greater, affects 43.9% of women and 49.5% of men in the US. Approximately 19.7% of patients treated for hypertension have apparent resistant hypertension (...
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