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FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions
The U.S. Food and Drug Administration today is requiring safety labeling changes for a class of antibiotics called fluoroquinolones to strengthen the warnings about the risks of mental health side effects and serious blood sugar disturbances, and make these warnings more consistent across the...
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Anticoagulant Comparison Chart
After being diagnosed with a blood clot, navigating the different medications can be confusing. NATF has designed a chart comparing the different anticoagulant medications, which include warfarin and the direct oral anticoagulants (DOACs).
This is a great tool for patients to use when...
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Management of Carpal Tunnel Syndrome Evidence-Based Clinical Practice Guideline
Overview
This clinical practice guideline is based on a systematic review of published studies with regard to the diagnosis and treatment of carpal tunnel syndrome (CTS). In addition to providing practice recommendations, this guideline also highlights limitations in the...
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Final Recommendation Statement: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions
Importance
The USPSTF uses the term “unhealthy alcohol use” to define a spectrum of behaviors, from risky drinking to alcohol use disorder (AUD) (eg, harmful alcohol use, abuse, or dependence) (...
Chapter 16: Pertussis
Pertussis, or whooping cough, is an acute infectious disease caused by the bacterium Bordetella pertussis. Outbreaks of pertussis were first described in the 16th century, and the organism was first isolated in 1906.
In the 20th century, pertussis was one of the most common...
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Pharmacotherapy for Adults With Alcohol Use Disorder (AUD) in Outpatient Settings
Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects of medications in adults with alcohol use disorder (AUD). The ...
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Lack of evidence for cannabis in adults with chronic neuropathic pain
Bottom Line:
There was no high-quality evidence for the efficacy of any CBM (herbal cannabis, plant-derived tetrahydrocannabinol (THC) (dronabinol), synthetic THC (nabilone), plant-derived THC/cannabidiol (CBD) com bination) in any condition with chronic neuropathic pain. The studies were...
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Drug Threat Bulletin: DSUVIA (Sufentanil)
The US Food and Drug Administration (FDA) approved DSUVIA, the synthetic opioid sufentanil in tiny blue tablet form, on Nov. 2, 2018 for single doses ingested under the tongue. Sufentanil is chemically similar to fentanyl (the lethal narcotic showing up as fake oxycodone pills and as a cutting...
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Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
BACKGROUND:
Baloxavir marboxil is a selective inhibitor of influenza cap-dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains resistant to current antiviral agents.
METHODS:
We conducted two...
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